Hui, Jie Dong, Pu‐Ting Liang, Lijia Mandal, Taraknath Li, Junjie Ulloa, Erlinda R. Zhan, Yuewei Jusuf, Sebastian Zong, Cheng Seleem, Mohamed N.
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Published in
Advanced Science
In article number https://doi.org/10.1002/advs.201903117 , Ji‐Xin Cheng and co‐workers report an endogenous chromophore‐based phototherapy platform to combat antibiotic‐resistance Staphylococcus aureus infections. Functional membrane microdomains of Staphylococcus aureus are catastrophically disrupted via photochemical decomposition of membrane‐bou...
Hui, Jie Dong, Pu-Ting Liang, Lijia Mandal, Taraknath Li, Junjie Ulloa, Erlinda R Zhan, Yuewei Jusuf, Sebastian Zong, Cheng Seleem, Mohamed N
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Published in
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Confronted with the rapid evolution and dissemination of antibiotic resistance, there is an urgent need to develop alternative treatment strategies for drug-resistant pathogens. Here, an unconventional approach is presented to restore the susceptibility of methicillin-resistant S. aureus (MRSA) to a broad spectrum of conventional antibiotics via ph...
Agrež, Vid Petkovšek, Rok
A highly adaptable fiber laser with pulse-on-demand and precision pulse-duration tuning is presented. It is based on a compact optical design combining the gain-switching technique with the all-fiber master oscillator and pump-recovery amplifier architecture. The approach of laser-pulse stability control by compensation pumping and pulse-duration c...
Satyanarayana, G. Narayana, K. L. Rao, B. Nageswara Slobodyan, M. S. Elkin, M. A. Kiselev, A. S.
Published in
Thermal Engineering
AbstractIn recent years use of Zr-Nb alloys has increased in nuclear and chemical industry due to its corrosion resistance and enhanced strength compared to tin based ones. Welding of zirconium alloys is one of the most critical manufacturing processes for nuclear assembly production. To select suitable welding parameters to achieve quality weld, u...
Petelin, Jaka Podobnik, Boštjan Petkovšek, Rok
A low-power source, such as a gain-switched laser diode, usually requires several amplification stages to reach sufficient power levels. When operating in burst mode, a correct input burst shape must be determined in order to compensate for gain saturation of all amplifier stages. In this paper we report on closed-form equations that enable saturat...
Petkovšek, Rok Novak, Vid Agrež, Vid
We report on a concept of a fiber MOPA based quasi-CW laser working at high modulation bandwidths up to 40 MHz capable of producing arbitrary pulse durations at arbitrary repetition rates. An output power of over 100 W was achieved and an on-off contrast of 25 dB. The laser features a dual-channel (dual-wavelength) seed source, a double stage YDF a...
Teutle-Coyotecatl, Bernardo Contreras-Bulnes, Rosalía Scougall-Vilchis, Rogelio J Almaguer-Flores, Argelia García-Pérez, Victor I Rodríguez-Vilchis, Laura Emma Arenas-Alatorre, Jesús A
Published in
Photomedicine and laser surgery
Objective: To determine surface roughness caused by Er:YAG laser irradiation and its effect on the increase in bacterial adhesion. Background: Er:YAG laser was proposed as a strategic device to reduce caries by its ability to generate chemical and structural changes in tooth enamel; in turn, it produces undesirable effects on the tooth surface that...
Krawinkel, Judith Torres-Mapa, Maria Leilani Mhatre, Eisha Kovács, Ákos T Heisterkamp, Alexander
Published in
Journal of biophotonics
There is a huge interest in developing strategies to effectively eliminate biofilms due to their negative impact in both industrial and clinical settings. In this study, structural damage was induced on two day-old B. subtilis biofilms using the interaction of 532 nm pulsed laser with gold thin films. Radiant exposure of 225 mJ/cm2 induced distinct...
Saklayen, Nabiha Huber, Marinus Madrid, Marinna Nuzzo, Valeria Vulis, Daryl I Shen, Weilu Nelson, Jeffery McClelland, Arthur A Heisterkamp, Alexander Mazur, Eric
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Published in
ACS nano
Efficiently delivering functional cargo to millions of cells on the time scale of minutes will revolutionize gene therapy, drug discovery, and high-throughput screening. Recent studies of intracellular delivery with thermoplasmonic structured surfaces show promising results but in most cases require time- or cost-intensive fabrication or lead to un...
Ganguly, Mohit Miller, Stephanie Mitra, Kunal
Published in
Lasers in surgery and medicine
Finite element models (continuum and vascular) were developed that can be used to predict temperature rise and quantify the thermal dose resulting from laser irradiation of excised rat skin samples and live anesthetized mouse tissue. The vascular model incorporating blood perfusion effects predicted temperature rise better in the live animal tissue...