Tilley, Dana M Lietz, Christopher B Cedeno, David L Kelley, Courtney A Li, Lingjun Vallejo, Ricardo
Published in
Neuromodulation : journal of the International Neuromodulation Society
Spinal cord stimulation (SCS) provides relief for patients suffering from chronic neuropathic pain although its mechanism may not be as dependent on electrical interference as classically considered. Recent evidence has been growing regarding molecular changes that are induced by SCS as being a key player in reversing the pain process. Here, we obs...
Sun, Yu Li, Bingshu Lu, Danhua Liu, Cheng Hong, Shasha Hong, Li
Published in
Female pelvic medicine & reconstructive surgery
The purpose of this study was to study the expression of adenosine diphosphate ribosylation factor GTPase-activating protein 3 (ArfGAP3) in the anterior vaginal wall of patients with pelvic organ prolapse (POP). From July 2016 to July 2018, the anterior vaginal wall of 31 POP patients (pelvic organ prolapse quantification [POP-Q] II-III [n = 10] an...
Skrt, Ana
Meng, Yi Wu, Hongyan Yao, Yongzhong Li, Rong
Published in
Gland Surgery
Background The purpose of this study is to investigate the association between protein expression of programmed death-ligand 1 (PD-L1) and the clinicopathological features of patients with invasive breast cancer. Methods Clinicopathological data of 651 patients with invasive breast carcinoma were collected over a 1-year period. Patients whose breas...
Uotila, Pyry M Lemma, Siria A Haapasaari, Kirsi-Maria Porvari, Katja Skarp, Sini Soini, Ylermi Jantunen, Esa Turpeenniemi-Hujanen, Taina Kuittinen, Outi
Published in
Hematology (Amsterdam, Netherlands)
ABSTRACT Objectives: To investigate the protein expression of the epithelial-mesenchymal transition-inducing transcription factors (TFs) Twist, ZEB1 and Slug in peripheral T-cell lymphomas (PTCL) and their correlation with clinical parameters. Methods: The expression of these TFs was studied in 53 diagnostic biopsy specimens of several different PT...
Lee, Chen-Hsiang Chuah, Seng-Kee Chang, Chia-Chi Chen, Fang-Ju
Published in
Pathogens
Hypermucoviscosity phenotypic Klebsiella pneumoniae (HV- Kp ) serotype K1 is the predominant pathogen of a pyogenic liver abscess, an emerging infectious disease that often complicates septic metastatic syndrome in diabetic patients with poor sugar control. HV- Kp isolates were more resistant to neutrophil phagocytosis than non-HV- Kp isolates beca...
Agana, Bernice A. Wysocki, Vicki H. Schoenberg, Daniel R.
Published in
Open Biology
The m7G cap marks the 5′ end of all eukaryotic mRNAs, but there are also capped ends that map downstream within spliced exons. A portion of the mRNA transcriptome undergoes a cyclical process of decapping and recapping, termed cap homeostasis, which impacts the translation and stability of these mRNAs. Blocking cytoplasmic capping results in the ap...
Davydenko, Svetlana Meledina, Tatiana Mittenberg, Alexey Shabelnikov, Sergey Vonsky, Maksim Morozov, Artyom
Published in
Bioengineering
Yeast strains are convenient models for studying domestication processes. The ability of yeast to ferment carbon sources from various substrates and to produce ethanol and carbon dioxide is the core of brewing, winemaking, and ethanol production technologies. The present study reveals the differences among yeast strains used in various industries. ...
Cinicola, Bianca Uva, Andrea Leonardi, Lucia Moratto, Daniele Giliani, Silvia Carsetti, Rita Ferrari, Simona Zicari, Anna Maria Duse, Marzia
Published in
Frontiers in Immunology
X-linked Agammaglobulinemia (XLA) is a rare genetic disorder of B-lymphocyte differentiation, characterized by the absence or paucity of circulating B cells, markedly reduced levels of all serum immunoglobulin isotypes and lack of specific antibody production. Bruton Tyrosine Kinase ( BTK ) gene encodes a cytoplasmic tyrosine kinase involved in the...
Xu, Yayun Chen, Feihu
Published in
Frontiers in Cell and Developmental Biology
Acid-sensing ion channels (ASICs) are members of the degenerin/epithelial sodium channel superfamily. They are extracellular pH sensors that are activated by protons. Among all ASICs, ASIC1a is one of the most intensively studied isoforms because of its unique ability to be permeable to Ca2+. In addition, it is considered to contribute to various p...
