Dynamic transcriptome changes during adipose tissue energy expenditure reveal critical roles for long noncoding RNA regu...
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10.1371/journal.pbio.2002176 / PLoS Biology / 15 / 8 / e2002176
Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape ge...
10.1371/journal.pgen.1006890 / PLoS Genetics / 13 / 7 / e1006890
GLIPR1 modulates the response of cisplatin-resistant human lung cancer cells to cisplatin
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10.1371/journal.pone.0182410 / PLoS ONE / 12 / 8 / e0182410
Crystal structure of the Dengue virus methyltransferase bound to a 5?-capped octameric RNA
10.1371/journal.pone.0012836 / PLoS ONE / 5 / 9 / 1-9
Methionine sulfoxide reductases protect Ffh from oxidative damages in Escherichia coli.
Published in The EMBO journal
In proteins, methionine residues are primary targets for oxidation. Methionine oxidation is reversed by methionine sulfoxide reductases A and B, a class of highly conserved enzymes. Ffh protein, a component of the ubiquitous signal recognition particle, contains a methionine-rich domain, interacting with a small 4.5S RNA. In vitro analyses reported...
Conserved sequences in the β subunit of archaeal and eukaryal translation initiation factor 2 (elF2), absent from elF5, ...
The eukaryotic translation initiation factor 2 (eIF2) binds the methionyl-initiator tRNA in a GTP-dependent mode. This complex associates with the 40 S ribosomal particle, which then, with the aid of other factors, binds to the 5' end of the mRNA and migrates to the first AUG codon, where eIF5 promotes GTP hydrolysis, followed by the formation of t...
Conserved sequences in the β subunit of archaeal and eukaryal translation initiation factor 2 (elF2), absent from elF5, ...
The eukaryotic translation initiation factor 2 (eIF2) binds the methionyl-initiator tRNA in a GTP-dependent mode. This complex associates with the 40 S ribosomal particle, which then, with the aid of other factors, binds to the 5' end of the mRNA and migrates to the first AUG codon, where eIF5 promotes GTP hydrolysis, followed by the formation of t...
Conserved sequences in the β subunit of archaeal and eukaryal translation initiation factor 2 (elF2), absent from elF5, ...
The eukaryotic translation initiation factor 2 (eIF2) binds the methionyl-initiator tRNA in a GTP-dependent mode. This complex associates with the 40 S ribosomal particle, which then, with the aid of other factors, binds to the 5' end of the mRNA and migrates to the first AUG codon, where eIF5 promotes GTP hydrolysis, followed by the formation of t...
Conserved sequences in the β subunit of archaeal and eukaryal translation initiation factor 2 (elF2), absent from elF5, ...
The eukaryotic translation initiation factor 2 (eIF2) binds the methionyl-initiator tRNA in a GTP-dependent mode. This complex associates with the 40 S ribosomal particle, which then, with the aid of other factors, binds to the 5' end of the mRNA and migrates to the first AUG codon, where eIF5 promotes GTP hydrolysis, followed by the formation of t...
Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation
Hrp1p is a heterogeneous ribonucleoprotein (hnRNP) from the yeast Saccharomyces cerevisiae that is involved in the cleavage and polyadenylation of the 3'-end of mRNAs and mRNA export. In addition, Hrp1p is one of several RNA-binding proteins that are posttranslationally modified by methylation at arginine residues. By using-functional recombinant H...
