Hanson, Heidi A Martin, Christopher O'Neil, Brock Leiser, Claire L Mayer, Erik N Smith, Ken R Lowrance, William T
Published in
The Journal of urology
There is a differential in prostate cancer mortality between black and white men. Advances in precision medicine have shifted the research focus toward underlying genetic differences. However, nonbiological factors may have a large role in these observed disparities. Therefore, we sought to measure the relative importance of race compared to health...
Mahal, Amandeep R Butler, Santino Franco, Idalid Muralidhar, Vinayak Larios, Dalia Pike, Luke R G Zhao, Shuang G Sanford, Nina N Dess, Robert T Feng, Felix Y
...
Published in
Cancer
Management for men aged ≤55 years with low-risk prostate cancer (LRPC) is debated given quality-of-life implications with definitive treatment versus the potential missed opportunity for cure with conservative management. The objective of this study was to define rates of conservative management for LRPC and associated short-term outcomes in young ...
Lindberg, Antti Talala, Kirsi Kujala, Paula Stenman, Ulf-Håkan Taari, Kimmo Kilpeläinen, Tuomas P Tammela, Teuvo L Auvinen, Anssi
Published in
International journal of cancer
More information is needed about effects of prostate-specific antigen (PSA) screening for informed decision making. The objective of our study is to evaluate the effects of an implemented screening decision on the risk of prostate cancer (PC) diagnosis and PC death. In a randomized trial, 31,867 Finnish men aged 55-67 years were allocated to the sc...
Lee, Jongsoo Kim, Ha Yan Goh, Hyeok Joon Heo, Ji Eun Almujalhem, Ahmad Alqahtani, Ali A Chung, Doo Yong Chang, Kidon Choi, Young Deuk Rha, Koon Ho
...
Published in
The Journal of urology
We compared early continence recovery after surgical treatment of prostate cancer with Retzius sparing robot-assisted radical prostatectomy and conventional robot-assisted radical prostatectomy. Robot-assisted radical prostatectomy was done by a single surgeon in 1,863 cases between October 2005 and May 2018 using the conventional and the Retzius s...
Gulati, Roman Psutka, Sarah P Etzioni, Ruth
Published in
The Journal of urology
Shared patient-physician decision-making regarding treatment for prostate cancer detected by prostate-specific antigen screening involves a complex calculus weighing the risk of the cancer and patient life expectancy. We investigated quantifying these competing risks using the probability that the cancer was "overdiagnosed"-i.e., would not have bee...
Burns, John F Hurwitz, Lauren M Levie, Katherine E Caumont, Fernando Brand, Timothy C Rosner, Inger L Stroup, Sean Musser, John E Cullen, Jennifer Porter, Christopher R
...
Published in
The Journal of urology
The aim of this study was to identify the effects of subsequent prostate needle biopsies after the baseline biopsy on health related quality of life with time. We compared men with and without prostate cancer, and men who did and did not undergo followup prostate needle biopsy. Included in analysis were patients enrolled in the Center for Prostate ...
chung, doo yong lee, jong soo goh, hyeok jun koh, dong hoon kim, min seok jang, won sik choi, young deuk
thus we suggest that active treatment is needed in these patients. In addition, patients with high-grade bGS should be managed aggressively, even if they show pGS downgrade.
Echevarria, Michelle I Awasthi, Shivanshu Cheng, Chia-Ho Berglund, Anders E Rounbehler, Robert J Gerke, Travis A Takhar, Mandeep Davicioni, Elai Klein, Eric A Freedland, Stephen J
...
Published in
The Journal of urology
Most prostate cancer in African American men lacks the ETS (E26 transforming specific) family fusion event (ETS-). We aimed to establish clinically relevant biomarkers in African American men by studying ETS dependent gene expression patterns to identified race specific genes predictive of outcomes. Two multicenter cohorts of a total of 1,427 men w...
Morais, Cátia Iracema Lobo, João Barreto, João P. Lobo, Cláudia Gonçalves, Nuno D.
Published in
Journal of Laboratory Medicine
Background Neuroendocrine differentiation of prostatic carcinoma is a rare entity associated with metastatic castration-resistant disease. Among useful biomarkers of neuroendocrine differentiation, chromogranin A, serotonin, synaptophysin and neuron-specific enolase stand out, while total prostate-specific antigen (PSA) levels are often low or unde...
Falagario, Ugo G Beksac, Alp Tuna Martini, Alberto Cumarasamy, Shivaram Gupta, Akriti Prasad, Sonya Thulasidass, Hari Shah, Qainat N Jayaratna, Isuru Lewis, Sara
...
Published in
The Journal of urology
We determined whether prostate multiparametric magnetic resonance imaging and genomic biomarkers might help further define patients with favorable intermediate risk prostate cancer which could safely considered suitable for active surveillance. From our institutional database we identified 509 patients who underwent radical prostatectomy with preop...
