Russell, Nicholas Allebone, James Dandash, Orwa Hoermann, Rudolf Cheung, Ada S Zajac, Jeffrey D Handelsman, David J Kanaan, Richard A Grossmann, Mathis
Published in
Clinical endocrinology
Roles for estradiol in modulating cognition in men remain uncertain. We assessed the isolated effects of estradiol on cognition in men in the absence of testosterone. Randomized trial of transdermal estradiol 0.9 mg daily, or matched placebo, for 6 months, hypothesizing that estradiol would improve verbal learning, verbal memory, and spatial proble...
Wada, Kento Tsuda, Takeshi Hanada, Yukiko Maeda, Yohei Mori, Kiyoshi Nishimura, Hiroshi
Published in
Ear, nose, & throat journal
Prostate cancer (PC) is prone to bone metastases, but very rarely it can spread to soft tissues. In the head and neck region, PC can metastasize to the orbital soft tissue, causing various symptoms such as vision loss. In this report, we describe the case of a 79-year-old man with PC metastasis in the orbital apex. He presented to an ophthalmologis...
Oehrlein, Nathan Streicher, Samantha A Kuo, Huai-Ching Chaurasia, Avinash McFadden, Jacob Nousome, Darryl Chen, Yongmei Stroup, Sean P Musser, John Brand, Timothy
...
Published in
Cancer medicine
There is substantial variability in prostate cancer (PCa) mortality rates across Caucasian American (CA), African American (AA), Asian, and Hispanic men; however, these estimates are unable to disentangle race or ethnicity from confounding factors. The current study explores survival differences in long-term PCa outcomes between self-reported AA an...
Pan, Yang Wang, Shangren Liu, Li Liu, Xiaoqiang
Published in
Frontiers in Oncology
Background We aimed to conduct a systematic review and meta-analysis of studies reporting functional and oncologic outcomes of combining whole-gland high-intensity focused ultrasound ablation (HIFU) with transurethral resection of the prostate (TURP) in prostate cancer (PCa) patients. Methods PubMed, Embase, Web of Science, Scopus, and Cochrane Lib...
Oake, Justin D Shiff, Benjamin Harasemiw, Oksana Tangri, Navdeep Ferguson, Thomas W Bhindi, Bimal Saranchuk, Jeff W Bansal, Rahul K Drachenberg, Darrel E Nayak, Jasmir G
...
Published in
The Journal of urology
The comparative effectiveness of radical prostatectomy (RP) versus radiation therapy (RT) for prostate cancer remains a largely debated topic. Utilizing a provincial population-based linked data set from an equal-access, universal health care system, we sought to compare outcomes among patients treated with either radiation or prostatectomy for non...
Zhu, Lina Gao, Ge Zhu, Yi Han, Chao Liu, Xiang Li, Derun Liu, Weipeng Wang, Xiangpeng Zhang, Jingyuan Zhang, Xiaodong
...
Published in
Frontiers in Oncology
Purpose To develop a cascaded deep learning model trained with apparent diffusion coefficient (ADC) and T2-weighted imaging (T2WI) for fully automated detection and localization of clinically significant prostate cancer (csPCa). Methods This retrospective study included 347 consecutive patients (235 csPCa, 112 non-csPCa) with high-quality prostate ...
Kohada, Yuki Kuromoto, Akito Takeda, Kazuya Iwamura, Hiromichi Atobe, Yuri Ito, Jun Kaifu, Tomonori Kaiho, Yasuhiro Nakashima, Ichiro Hinata, Nobuyuki
...
Published in
Frontiers in Urology
Introduction This study aims to investigated for the first time the role of myeloid-derived suppressor cells (MDSCs) in metastatic-hormone sensitive prostate cancer (mHSPC), which has not been investigated previously. Materials and methods This was a prospective observational cohort study. MDSC subsets in peripheral blood samples were classified an...
Abbasi-Kangevari, Mohsen Saeedi Moghaddam, Sahar Ghamari, Seyyed-Hadi Azangou-Khyavy, Mohammadreza Malekpour, Mohammad-Reza Rezaei, Negar Rezaei, Nazila Kolahi, Ali-Asghar Amini, Erfan Mokdad, Ali H.
...
Published in
Frontiers in Oncology
Background Prostate cancer (PCa) is the second most prevalent cancer among men worldwide. This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East us...
Liu, Fei Shi, Xiaolei Wang, Fangming Han, Sujun Chen, Dong Gao, Xu Wang, Linhui Wei, Qiang Xing, Nianzeng Ren, Shancheng
...
Published in
Frontiers in Oncology
Background and objectives Prostate specific antigen (PSA) is currently the most commonly used biomarker for prostate cancer diagnosis. However, when PSA is in the gray area of 4-10 ng/ml, the diagnostic specificity of prostate cancer is extremely low, leading to overdiagnosis in many clinically false-positive patients. This study was trying to disc...
Marenghi, Cristina Qiu, Zhuyu Helleman, Jozien Nieboer, Daan Rubio-Briones, Josè Carroll, Peter R Lee, Lui Shiong Valdagni, Riccardo Boutros, Paul C Nicolai, Nicola
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BackgroundLittle is known about the consequences of delaying radical prostatectomy (RP) after Active Surveillance (AS) according to stringent or wider entry criteria. We investigated the association between inclusion criteria and rates, and timing of adverse pathological findings (APFs) among patients in GAP3 cohorts.MethodsAPFs (GG ≥ 3, pT ≥ 3, pN...
