Cerebrovascular Reactivity Impairment in Preclinical Alzheimer's Disease.
Published in Journal of neuroimaging : official journal of the American Society of Neuroimaging
A substantial overlap exists between declines in cerebral vasoreactivity (CVR) and symptomatic Alzheimer's disease (AD). CVR can be quantified using transcranial Doppler (TCD) measurement of cerebral blood flow velocities (CBFV) in the middle cerebral artery (MCA) with CO2 as a vasodilatory stimulus. The breath-hold acceleration index (BHAI) is a n...