We address advances in the understanding of myometrial physiology, focusing on excitation and the effects of gestation on ion channels and their relevance to labor. This review moves through pioneering studies to exciting new findings. We begin with the myometrium and its myocytes and describe how excitation might initiate and spread in this myogen...
Published in Frontiers in Cardiovascular Medicine
Potassium is the predominant intracellular cation, with its extracellular concentrations maintained between 3. 5 and 5 mM. Among the different potassium disorders, hypokalaemia is a common clinical condition that increases the risk of life-threatening ventricular arrhythmias. This review aims to consolidate pre-clinical findings on the electrophysi...
Potassium (K) deficiency is a rather common situation which impacts negatively on biomass, photosynthesis and N assimilation, making K fertilization often unavoidable. Effects of K deficiency have been investigated for several decades and recently, progress has been made in identifying metabolomics signatures thereby offering potential to monitor t...
ABSTRACT The Maranhão floodplain is dominated by native grasses like capim-açú (Paspalum plicatulum, Mich.). Due to scarce information on nutrient demands of native species, farmers are replacing native pastures by exotic and potentially invasive species such as antelope grass (Echinochloa pyramidalis, Lam). The aim of this study was to compare the...
Published in Physiological Reports
Dietary sodium deprivation activates aldosterone‐sensitive neurons and causes sodium appetite. Potassium greatly influences aldosterone levels in sodium‐deprived rats. The activation of aldosterone‐sensitive neurons does not correlate with plasma potassium. Sodium appetite does not require increased plasma potassium. In sodium‐deprived rats, increa...
Published in Nutrients
Despite decades of efforts to reduce sodium intake, excess dietary sodium remains commonplace, and contributes to increased cardiovascular morbidity and mortality independent of its effects on blood pressure. An increasing amount of research suggests that high-sodium diets lead to reduced nitric oxide-mediated endothelial function, even in the abse...
Published in Nutrients
We explored the dose-response relations of sodium, potassium, magnesium and calcium with cardiovascular disease (CVD) risk in the Framingham Offspring Study, as well as the combined effects of these minerals. Analyses included 2362 30–64 year-old men and women free of CVD at baseline. Cox proportional-hazards models were used estimate adjusted haza...
Published in Kidney International Reports
Published in Frontiers in Plant Science
Waterlogging occurs frequently at the stem elongation stage of wheat in southern China, decreasing post-anthesis photosynthetic rates and constraining grain filling. This phenomenon, and the mitigating effect of nutrient application, should be investigated as it could lead to improved agronomic guidelines. We exposed pot-cultured wheat plants at th...
Published in Experimental and therapeutic medicine
Hemodialysis is a method for the renal replacement therapy followed by series of acute and chronic complications. Dyselectrolytemia appears in patients undergoing dialysis through mechanisms related to the chronic kidney disease and/or to the dialysis therapy and for this group of patients it is associated with an increase of morbidity and mortalit...
