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Acute Administration of Desformylflustrabromine Relieves Chemically Induced Pain in CD-1 Mice.

Published in Molecules (Basel, Switzerland)

Neuronal nicotinic acetylcholine receptors are cell membrane-bound ion channels that are widely distributed in the central nervous system. The α4β2 subtype of neuronal nicotinic acetylcholine receptor plays an important role in modulating the signaling pathways for pain. Previous studies have shown that agonists, partial agonists, and positive allo...