Molecules (Basel, Switzerland)
The treatment of diabetes lies in developing novel functional carriers, which are expected to have the unique capability of monitoring blood glucose levels continuously and dispensing insulin correctly and timely. Hence, this study is proposing to create a smart self-regulated insulin delivery system according to changes in glucose concentration. T...
Frontiers in Materials
Light-responsive hydrogel actuators show attractive biomedical applications for in vivo drug delivery tool, surgical tissue repair operation, and vascular cleaning due to its non-contact, rapid, precise, and remote spatial control of light. Conventional visible–light–responsive hydrogels contain special chemical structure or groups, and the difficu...
Regulating catalytic activity plays an important role in further optimizing and developing multifunctional catalysts with high selectivity and high activity. Reversible dual regulation of catalytic activity has always been a challenging task. Here, we prepared poly(N-isopropylacrylamide)-anchored gold nanoparticles ([email protected]) through hos...
Thermogelling hydrogels, such as poly( N -isopropylacrylamide) [P(NiPAAm)], provide tunable constructs leveraged in many regenerative biomaterial applications. Recently, our lab developed the crosslinker poly(glycolic acid)-poly(ethylene glycol)-poly(glycolic acid)-di(but-2-yne-1,4-dithiol), which crosslinks P(NiPAAm-co-glycidyl methacrylate) via t...
Macromolecular rapid communications
A series of poly(N-isopropylacrylamide) (PNIPAm) homopolymers with narrow molecular weight distributions (MWDs) is prepared via photoinduced electron/energy transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization. The thermal transition temperature of these polymer samples is analyzed via turbidity measurements in water/...
Science and technology of advanced materials
A variety of poly(N-isopropylacrylamide) (PIPAAm)-grafted surfaces have been reported for temperature-controlled cell adhesion/detachment. However, the surfaces reported to date need further improvement to achieve good outcomes for both cell adhesion and detachment, which are inherently contradictory behaviors. This study investigated the effects o...
A previous report shows that poly(N-isopropylacrylamide) (PIPAAm) gel grafted onto poly(dimethylsiloxane) (PDMS) (PI-PDMS) surfaces with large PIPAAm graft density (Lar-PI-PDMS), is prepared by using electron beam irradiation, demonstrating that applied mechanical stretching affects properties of the Lar-PI-PDMS surface. However, the influence of P...
Preparation of thermoresponsive glass sphere-based composite carriers via bottom-spray coating technology.
Underwater robots and vehicles have received great attention due to their potential applications in remote sensing and search and rescue. A challenge for micro aquatic robots is the lack of small motors needed for three-dimensional locomotion in water. Here, we show a simple diving and surfacing device fabricated from thermo-sensitive poly(N-isopro...
ACS applied materials & interfaces
Poly(N-isopropylacrylamide) (pNIPAM) hydrogels have broad potential applications as drug delivery vehicles because of their thermoresponsive behavior. pNIPAM loading/release performances are directly affected by the gel network structure. Therefore, there is a need with the approaches for accurate design of 3D pNIPAM assemblies with the structure o...