Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes
Published in Frontiers in Microbiology
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus. Here, we hypothesized that liposomes are capable of neutralizing cytolytic virulence factors se...
