Deformation predictions in high Concrete Face Rockfill Dams tend to underestimate observed settlements due to scale effect and breakage phenomena that cannot be adequately captured by laboratory tests. This paper presents a Visco-Elasto-Perfectly Plastic (VEPP) model for predicting deformations in high Concrete Face Rockfill Dams (CFRDs) that addre...
Published in Frontiers in Molecular Neuroscience
Impaired mitochondrial function has been associated with the onset of neurodegenerative diseases. Specifically, certain mitochondrial toxins, such as 3-nitropropionic acid (3-NP), initiate cellular changes within the striatum that closely resemble the pathology observed in Huntington’s disease (HD). Among the pivotal signaling molecules contributin...
The effect of hot rolling on the microstructure, mechanical, and corrosion properties of the magnesium alloy 96 wt% Mg–2.3 wt% Zn–0.7 wt% Ca–1 wt% Mn was studied. After heat treatment, the original plates of an as-cast alloy were rolled from a 7 mm thickness to a 0.2 mm thickness at two temperatures—300 or 400 °C. It has been established that incre...
Published in Modelling and Simulation in Materials Science and Engineering
Exploring the vast compositional space of high-entropy alloys (HEAs) promises materials with superior mechanical properties much needed in industrial applications. We demonstrate on the 7-component alloy AlVCrFeCoNiMo system with randomly ordered atoms that this exploration of the compositional space can be accelerated by combining molecular dynami...
Los nuevos heridos de Malabou, obra que revisa y actualiza el corpus freudiano sobre el trauma, expone un diagnóstico de la desafección contemporánea: la violencia hoy se presenta como si no tuviese sentido y es la exposición a este daño que es, en realidad, relacional el que constituye subjetividades desafectivas. Uno de los traumas sociopolíticos...
Published in Frontiers in Molecular Neuroscience
Introduction The TrkB receptor is known for its role in regulating excitatory neuronal plasticity. However, accumulating evidence over the past decade has highlighted the involvement of TrkB in regulating inhibitory synapse stability and plasticity, particularly through regulation of the inhibitory scaffold protein gephyrin, although with contradic...
In this study, the high-temperature deformation behaviour of the UNS S32750 Super Duplex Stainless Steel (SDSS) alloy was investigated by means of deformability and microstructure evolution in the (1050–1200) °C temperature (T) range. The deformability of the UNS S32750 SDSS alloy was investigated by the up-setting method using a gravity-drop hamme...
Plastic mulches, fertilizers and pesticides have been extensively employed in agriculture to increase crop yields, though it has also led to the inadvertent accumulation of them over time. These accumulations have the potential to disrupt the soil ecological process and subsequently impact the plant community composition. Alien plants always benefi...
Isocitrate dehydrogenase wild-type glioblastoma, a Grade 4 malignant brain neoplasm, remains resistant to multimodal treatment, with a median survival of 16 months from diagnosis with no geographical bias. Despite increasing appreciation of intra-tumour genotypic variation and stem cell plasticity, such knowledge has yet to translate to efficacious...
Plant functional traits are effective indicators and predictors of environmental change, revealing plants’ ecological countermeasures and adaptability through phenotypic plasticity. We conducted a 6-year grazing experiment on typical temperate grassland to assess the impact of different grazing periods on the plasticity and variability of the funct...
