rolfo, alessandro cosma, stefano nuzzo, anna maria moretti, laura tancredi, annalisa canosa, stefano revelli, alberto benedetto, chiara
Background: Pregnancy has been identified as a risk factor for severe COVID-19, leading to maternal and neonatal complications. The safety and effects of the SARS-CoV-2 vaccination during pregnancy, particularly on placental function and oxidative stress (OxS), remain underexplored. We investigated the impact of vaccination on third-trimester place...
zhu, minting xiaotian, li lin, wei zeng, dan yang, pan weigui, ni chen, zhijian lin, bingyi lai, lijuan ouyang, zhongai
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Microplastics (MPs) are emerging environmental pollutants. Pregnancy and infancy are sensitive windows for environmental exposure. However, few studies have investigated the presence of MPs in mother–infant pairs, or the exposure source. In this study, nine mother–infant pairs were recruited, and samples of placenta, cord blood, and meconium were c...
Baker, Julie C.
The evolution of the placenta was transformative. It changed how offspring are fed during gestation from depositing all the resources into an egg to continually supplying resources throughout gestation. Placental evolution is infinitely complex, with many moving parts, but at the core it is driven by a conflict over resources between the mother and...
Piani, Federica Tossetta, Giovanni
Published in
Frontiers in Clinical Diabetes and Healthcare
lubecka, karolina chęciński, maciej chęcińska, kamila bliźniak, filip wach, tomasz szuta, mariusz chlubek, dariusz sikora, maciej
Objectives: This review aimed to gather and summarize the existing information on the clinical application of allogeneic umbilical and placental derivatives in the treatment of temporomandibular joint disorders. Methods: Research on the impact of the use of umbilical and placental derivatives on reducing pain and improving mobility in the temporoma...
de Sousa, Ashelley Kettyllem Alves Pires, Keyla Silva Nobre Cavalcante, Isadora Hart Cavalcante, Iasmin Cristina Lira Santos, Julia Domingues Queiroz, Maiara Ingrid Cavalcante Leite, Ana Catarina Rezende Crispim, Alessandre Carmo da Rocha Junior, Edmilson Rodrigues Aquino, Thiago Mendonça
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Published in
Frontiers in Endocrinology
Introduction Microplastics (MPs) are environmental pollutants that pose potential risks to living organisms. MPs have been shown to accumulate in human organs, including the placenta. In this study, we investigated the biochemical impact of 5 μm polystyrene microplastics (PS-MPs) on term placental chorionic villi explants, focusing on cytotoxicity,...
Kojima, Fumiaki Hioki, Yuka Sekiya, Hiroki Kashiwagi, Hitoshi Iizuka, Yoshiko Eto, Kei Maehana, Shotaro Kawakami, Fumitaka Kubo, Makoto Ishibashi, Hitoshi
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Published in
International journal of molecular sciences
Microsomal prostaglandin E synthase-1 (mPGES-1) is an isozyme of the prostaglandin (PG) E synthase that acts downstream of cyclooxygenase and catalyzes the conversion of PGH2 to PGE2. The impact of genetic deletion of mPGES-1 on the development of 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis, a well-established model of inflammatory b...
sypiańska, malwina stupak, aleksandra
Fetal growth restriction (FGR) is a disorder defined as the failure of a fetus to achieve its full biological development potential due to decreased placental function, which can be attributed to a range of reasons. FGR is linked to negative health outcomes during the perinatal period, including increased morbidity and mortality. Long-term health p...
Wang, Xintao Fang, Tingting Chen, Daiwen Pu, Junning Tian, Gang He, Jun Zheng, Ping Mao, Xiangbing Wu, Aimin Yu, Bing
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Published in
Frontiers in Veterinary Science
Maternal dietary supplementation with chitosan oligosaccharide (COS) has been considered as a potential intervention to mitigate the occurrence of intrauterine growth restriction (IUGR) and improve postnatal growth. The present study investigated the effect of COS as a dietary supplement for sows during late gestation and lactation on their product...
You, Yilan Qian, Zhiwen Jiang, Ying Chen, Lingyan Wu, Danping Liu, Lu Zhang, Feng Ning, Xin Zhang, Yan Xiao, Jianping
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Published in
Frontiers in Cell and Developmental Biology
Ferroptosis, a distinct form of non-apoptotic cell death characterized by iron dependency and lipid peroxidation, is increasingly linked to various pathological conditions in pregnancy and liver diseases. It plays a critical role throughout pregnancy, influencing processes such as embryogenesis, implantation, and the maintenance of gestation. A gro...
