De Silva, Theshani A Alphonsus, Lotus Ma, Christopher Hogan, Malcolm Sedano, Rocio Narula, Neeraj Danese, Silvio Peyrin-Biroulet, Laurent MacDonald, John K Singh, Siddharth
...
Published in
Journal of Crohn's & colitis
Treatment options for proctitis are limited. To assist trial design for novel therapeutics, we conducted a systematic review and meta-analysis of proctitis randomized controlled trials [RCTs] to quantify placebo rates and identify factors influencing them. We searched MEDLINE, EMBASE and CENTRAL from inception to June 2021. Placebo-controlled trial...
Haas, Julia W Rief, Winfried Weiß, Frauke Doering, Bettina K Kleinstäuber, Maria Ruwoldt, Sina Sarter, Lena Thomas, Ruth Rheker, Julia
Published in
Psychology, health & medicine
It is not only crucial to provide patients with information, but also to communicate this information in a way to enable patient participation in health decisions. Experimental studies investigating the association between the communication style of health professionals and patients' health decisions are rare, which limits causal conclusions. This ...
Page, Ann-Sophie; Verbakel, Jan Y; 42064; Verhaeghe, Johan; 2632; Latul, Yani P; Housmans, Susanne; 62423; Deprest, Jan; 31972;
OBJECTIVE: To assess whether CO2 laser treatment is more effective than sham application in relieving the most bothersome symptom (MBS) in women with genitourinary syndrome of menopause (GSM). DESIGN: Single-centre, sham-controlled, double-blind, randomised trial. SETTING: A tertiary centre in Belgium. POPULATION: Sixty women with moderate to sever...
Gaab, Jens
Published in
Frontiers in Psychology
Irving Kirsch’s work spans over four decades and provided science and clinical practice with as much invaluable insights in the inner workings of treatments as it provided us and patients with their rights and our duties. Here, two early publications of Irving Kirsch on the topic of psychotherapy and its relation to placebo are revised and put into...
Wan, Yingying Yang, Jiaxi Ma, Tianyue Wang, Wenqian Wang, Haonan Sun, Wenting Ye, Wanting Yang, Lin Kou, Qiuai
Published in
Frontiers in Pharmacology
Nishimura, Tatsuo Muta, Hiromi Hosaka, Taisuke Ueda, Makoto Kishida, Kazue
Published in
Acta paediatrica (Oslo, Norway : 1992)
The World Health Organization has listed honey as a potential treatment for coughs, but there is little evidence to support its use for coughs associated with upper respiratory tract infections (URTIs). This study evaluated how effective honey was for treating nocturnal coughs and sleep difficulties. This multicentre, randomised, double-blind, plac...
Lu, Yongkai Luo, Xiaoqin Yang, Di Li, Yi Gong, Tuotuo Li, Binglin Cheng, Jian Chen, Ruijuan Guo, Xin Yuan, Wei
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Published in
Frontiers in Oncology
Objectives Chemotherapy and radiotherapy generally cause serious adverse side effects in cancer patients, thereby affecting subsequent treatment. Numerous studies have shown that taking probiotics is an option for preventing and treating these side effects. In this investigation, a meta-analysis of the effects of oral probiotics on side effects bro...
Goje, Oluwatosin Sobel, Ryan Nyirjesy, Paul Goldstein, Steven R Spitzer, Mark Faught, Brooke Larson, Shelagh King, Thomas Azie, Nkechi E Angulo, David
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Published in
Journal of women's health (2002)
Background: Ibrexafungerp is a novel antifungal treatment for acute vulvovaginal candidiasis (VVC). Using pooled data from two phase three studies (VANISH 303 and 306) in the treatment of acute VVC, this analysis sought to determine the effectiveness of ibrexafungerp in various patient subgroups that may impact outcomes. Materials and Methods: Data...
Wan, Yingying Yang, Jiaxi Ma, Tianyue Wang, Wenqian Wang, Haonan Sun, Wenting Ye, Wanting Yang, Lin Kou, Qiuai
Published in
Frontiers in Pharmacology
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting females more than males. Clinical symptoms, disease activity and comorbidities are more severe in females. Moreover, the choice of treatment for females is limited during childbearing age due to the side effects of current drugs. Therefore, developing novel and safer ...
Chari, Aswin Lee, Keng Siang Alamri, Alexander Hutchinson, Peter J. A. Kolias, Angelos G. Edlmann, Ellie
Published in
Frontiers for Young Minds
Chronic subdural haematoma is the medical name for bleeding that occurs between the skull and the brain. It usually happens to older people, like grandparents. If it causes serious symptoms, brain surgeons will operate. However, even after surgery, chronic subdural haematomas can come back, and further operations may be needed. We tested whether a ...
