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Vigneaud, Julien Kohler, Annegret Sow, Mamadou Dia Delaunay, Alain Fauchery, Laure Guinet, Frederic Daviaud, Christian Barry, Kerrie W Keymanesh, Keykhosrow Johnson, Jenifer
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Published in
The New phytologist
Ectomycorrhizas are an intrinsic component of tree nutrition and responses to environmental variations. How epigenetic mechanisms might regulate these mutualistic interactions is unknown. By manipulating the level of expression of the chromatin remodeler DECREASE IN DNA METHYLATION 1 (DDM1) and two demethylases DEMETER-LIKE (DML) in Populus tremula...
Shonibare, Zainab Monavarian, Mehri O'Connell, Kathleen Altomare, Diego Shelton, Abigail Mehta, Shubham Jaskula-Sztul, Renata Phaeton, Rebecca Starr, Mark D Whitaker, Regina
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Published in
Cell reports
Growth factors in tumor environments are regulators of cell survival and metastasis. Here, we reveal the dichotomy between TGF-β superfamily growth factors BMP and TGF-β/activin and their downstream SMAD effectors. Gene expression profiling uncovers SOX2 as a key contextual signaling node regulated in an opposing manner by BMP2, -4, and -9 and TGF-...
