Published in Medical physics
All photon counting detectors have a characteristic count rate over which their performance degrades. Degradation in the clinical setting takes the form of increased noise, reduced material quantification accuracy, and image artifacts. Count rate is a function of patient attenuation, beam filtration, scanner geometry, and X-ray technique. To guide ...
Published in Physics in Medicine & Biology
Objective. Cone beam CT (CBCT) in preclinical small animal irradiation platforms provides essential information for image guidance and radiation dose calculation for experiment planning. This project developed a photon-counting detector (PCD)-based multi(3)-energy (ME-)CBCT on a small animal irradiator to improve the accuracy of material differenti...
Published in Journal of Physics: Conference Series
This study investigated the use of a built-in-self-test (BIST) module detecting catastrophic errors in photon-counter accumulator for liquid contamination level measurement. Efficient algorithms are exceptionally demanded for a high-count rate and low voltage system photon counting circuit on-chip. The photon counter sensors are also required high ...
Hydrodynamic cavitation was evaluated for its reactive oxygen species production in several convergent-divergent microchannel at the transition from micro to milli scale. Channel widths and heights were systematically varied to study the influence of geometrical parameters at the transitory scale. A photomultiplier tube was used for time-resolved p...
Published in Metrologia
The realization of the low light level illuminance scale of the National Institute of Metrology (NIM, China) is presented. Two methods were used to achieve the photometric scale covering (1 × 10−10–2 × 100) lx, the first method based on the luminance adjustable two-stage integrating sphere source was used to realize the illuminance scale down to 1 ...
Published in Frontiers in Physics
Underwater wireless optical communication is facing absorption, scattering problems, which, in principle, can be greatly resolved by underwater photon-counting communication (UPCC) technology that exhibits high-sensitivity communication characteristics in long-range underwater wireless optical communication. Recent studies on UPCC are mainly focuse...
Photon counting computed tomography scanners constitute a major improvement of the field of computed tomography, opening various prospective and enabling the decomposition of computed tomography images into different materials. The material decomposition algorithm, mapping photon counts to material pathlengths, relies on a forward model with Poisso...
This review article offers an overview of the differences between traditional energy integrating (EI) X-ray imaging and the new technique of X-ray photon counting spectral imaging (x-CSI). The review is motivated by the need to image gold nanoparticles (AuNP) in vivo if they are to be used clinically to deliver a radiotherapy dose-enhancing effect ...
Published in Frontiers in Bioengineering and Biotechnology
A superconducting transition edge sensor (TES) is an energy-dispersive single-photon detector that distinguishes the wavelength of each incident photon from visible to near-infrared (NIR) without using spectral dispersive elements. Here, we introduce an application of the TES technique for confocal laser scanning microscopy (CLSM) as proof of our c...
Published in Academic radiology
The purpose of this study was to investigate the potential of photon-counting CT (PCCT) to improve quantitative image quality for low dose imaging compared to energy-integrating detector CT (EID CT). An investigational scanner (Siemens, Germany) with PCCT and EID CT subsystems was used to compare image quality performance at four dose levels: 1.7, ...
