Hull, Thomas D Levine, Jacob Bantilan, Niels Desai, Angel N Majumder, Maimuna S
Published in
JMIR Formative Research
Background The novel COVID-19 disease has negatively impacted mortality, economic conditions, and mental health. These impacts are likely to continue after the COVID-19 pandemic ends. There are no methods for characterizing the mental health burden of the COVID-19 pandemic, and differentiating this burden from that of the prepandemic era. Accurate ...
Pujarula, Vijayalakshmi Pusuluri, Madhu Bollam, Srikanth Das, Roma Rani Ratnala, Rambabu Adapala, Gopikrishna Thuraga, Vishnukiran Rathore, Abhishek Srivastava, Rakesh K. Gupta, Rajeev
...
Published in
Frontiers in Plant Science
Nitrogen (N) is one of the primary macronutrients required for crop growth and yield. This nutrient is especially limiting in the dry and low fertility soils where pearl millet [ Pennisetum glaucum (L.) R. Br] is typically grown. Globally, pearl millet is the sixth most important cereal grown by subsistence farmers in the arid and semi-arid regions...
Marshall, Jesse D Aldarondo, Diego E Dunn, Timothy W Wang, William L Berman, Gordon J Ölveczky, Bence P
Published in
Neuron
In mammalian animal models, high-resolution kinematic tracking is restricted to brief sessions in constrained environments, limiting our ability to probe naturalistic behaviors and their neural underpinnings. To address this, we developed CAPTURE (Continuous Appendicular and Postural Tracking Using Retroreflector Embedding), a behavioral monitoring...
Reissig, Lukas F. Seyedian Moghaddam, Atieh Prin, Fabrice Wilson, Robert Galli, Antonella Tudor, Catherine White, Jaqueline K. Geyer, Stefan H. Mohun, Timothy J. Weninger, Wolfgang J.
...
Published in
Frontiers in Neuroanatomy
An essential step in researching human central nervous system (CNS) disorders is the search for appropriate mouse models that can be used to investigate both genetic and environmental factors underlying the etiology of such conditions. Identification of murine models relies upon detailed pre- and post-natal phenotyping since profound defects are no...
El-Hendawy, Salah Elsayed, Salah Al-Suhaibani, Nasser Alotaibi, Majed Tahir, Muhammad Usman Mubushar, Muhammad Attia, Ahmed Hassan, Wael M.
Published in
Plants
The application of proximal hyperspectral sensing, using simple vegetation indices, offers an easy, fast, and non-destructive approach for assessing various plant variables related to salinity tolerance. Because most existing indices are site- and species-specific, published indices must be further validated when they are applied to other condition...
Bollier, Norbert Andrade Buono, Rafael Jacobs, Thomas Nowack, Moritz
CRISPR technology is an established tool for the generation of knockout plants (Zhang et al., 2019), yet limitations remain. First, the manipulation of individual genes may fail to produce phenotypes for groups of genes with redundant or synergistic functions. While this has been partially addressed by multiplexing guide RNAs (gRNAs), there is conc...
Ey, Elodie De Chaumont, Fabrice Bourgeron, Thomas
In their natural habitat, mice interact and communicate to regulate major functions, such as reproduction, group coordination, and protection. Nevertheless, little is currently known about their spontaneous emission of ultrasonic vocalizations (USVs), despite their broad use as a phenotypic marker in mouse models of neuropsychiatric disorders. Here...
Wheless, Lee Baker, Laura Edwards, LaVar Anand, Nimay Birdwell, Kelly Hanlon, Allison Chren, Mary-Margaret
Published in
JMIR Medical Informatics
Background Studies involving organ transplant recipients (OTRs) are often limited to the variables collected in the national Scientific Registry of Transplant Recipients database. Electronic health records contain additional variables that can augment this data source if OTRs can be identified accurately. Objective The aim of this study was to deve...
Hufendiek, Karsten Hufendiek, Katerina Jägle, Herbert Stöhr, Heidi Book, Marius Spital, Georg Rustambayova, Günay Framme, Carsten Weber, Bernhard H. F. Renner, Agnes B.
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Published in
International Journal of Molecular Sciences
Autosomal recessive bestrophinopathy (ARB) has been reported as clinically heterogeneous. Eighteen patients (mean age: 22.5 years; 15 unrelated families) underwent ophthalmological examination, fundus photography, fundus autofluorescence, and optical coherence tomography (OCT). Molecular genetic testing of the BEST1 gene was conducted by the chain-...
Denaxas, Spiros Shah, Anoop D Mateen, Bilal A Kuan, Valerie Quint, Jennifer K Fitzpatrick, Natalie Torralbo, Ana Fatemifar, Ghazaleh Hemingway, Harry
Published in
JAMIA Open
Objectives The UK Biobank (UKB) is making primary care electronic health records (EHRs) for 500 000 participants available for COVID-19-related research. Data are extracted from four sources, recorded using five clinical terminologies and stored in different schemas. The aims of our research were to: (a) develop a semi-supervised approach for boots...
