Biogenesis and signalling requirements of plant receptor-like proteins mediating resistance to fungal pathogens
cum laude graduation
Towards generating broad-spectrum resistance to pathogens in plants: studies on a down-stream signalling NB-LRR of tomat...
On the involvement of host proteins in Cowpea mosaic virus intercellular spread
Abstract of thesis Paulus den Hollander entitled “On the involvement of host proteins in Cowpea mosaic virus intercellular spread”. Defence: 18th of November 13.30 h Abstract Intercellular spread of Cowpea mosaic virus (CPMV) occurs via movement tubules inserted into the cell wall spanning plasmodesmata (PD) channels. These tubules are composed sol...
Genome structure and pathogenicity of the fungal wheat pathogen Mycosphaerella graminicola
The phytopathogenic fungus Mycosphaerella graminicola (Fuckel) J. Schröt. in Cohn (asexual stage: Zymoseptoria tritici (Desm.) Quaedvlieg & Crous) causes septoria tritici leaf blotch (STB) in wheat and is one of the most important diseases of this crop worldwide. However, STB control, mainly based on the use of resistant cultivars and fungicides, i...
Ethylene perception and NEP-like protein production by Botrytis cinerea
Botrytis cinerea can infect more than 200 plant species, including a wide range of economically important crops. During pathogen infection, plants release ethylene and it has been hypothesized that ethylene may predispose host tissue for infection by inducing senescence and ripening. This thesis focused on the roles that ethylene production and per...
Functional Analysis of Cladosponum fulvum Effector Catalog
Onlangs is de DNA-sequentie van het genoom van Cladosporium fulvum bepaald. Het voornaamste doel daarvan is de identificatie en karakterisering van nieuwe effectors.
Homologues of Cladosporium fulvum effector proteins are present in species of Dothideomycetes, are recognized by cognate...
Tot nu toe werden effectoreiwitten van schimmels beschouwd als soortspecifiek en homologen van Cladosporium fulvum effectors werden nooit eerder aangetoond in andere schimmelsoorten. Nu is er bewijs gevonden voor het bestaan van homologe C. fulvum effectors in soorten van Dothideomycetes die pathogeen zijn op ver verwante monocotyle en dicotyle pla...
Genome-wide investigation into roles of Arabidosis receptor-like proteins in pathogen defense
Receptor-like proteins (RLPs) are receptors on the surface of plant cells that are important for the activation of disease resistance. Furthermore, some RLPs are important for plant development. The Arabidopsis genome contains 57 genes encoding RLPs. A genome wide collection of RLP gene knock-out mutants was assembled and functionally analyzed for ...
Structure, function and subcellular localization of the potato Resistance protein Rx1
Resistance proteins are part of the plant’s immune system and mediate a defence response upon recognizing their cognate pathogens. They are thought to be present in the cell as part of a larger protein complex. The modular architecture of R proteins suggests that they form a scaffold for various interacting proteins, involved in pathogen recognitio...
The Phytophthora infestans avirulence gene PiaAvr4 and its potato counterpart R4
The potato late blight disease that is caused by the oomycete pathogen Phytophthora infestans is a major threat for potato crops worldwide. In recent years research on oomycete plant pathogens was boosted by the availability of novel genomic tools and resources for several oomycete genera, such as Phytophthora, Hyaloperonospora, Pythium and Aphanom...
