Hamed, A. M. R. Abdel-Shafi, I. R. Elsayed, M. D. A. Mahfoz, A. M. Tawfeek, S. E. Abdeltawab, M. S. A.
Published in
Helminthologia
Background Curcumin exerts anti-oxidant and anti-inflammatory properties that have proven to be of value in the management of several parasitic infections. Objective Investigation of the value of curcumin in the management of trichinosis either alone or as an adjuvant to albendazole. Methods Animals received either curcumin 150 mg/kg, curcumin 300 ...
Holz, Olaf van Vorstenbosch, Robert Guenther, Frank Schuchardt, Sven Trinkmann, Frederik van Schooten, Frederik-Jan Smolinska, Agnieszka Hohlfeld, Jens M
Published in
Journal of Breath Research
It is still unclear how airway inflammation affects the breath volatile organic compounds (VOCs) profile in exhaled air. We therefore analyzed breath following well-defined pulmonary endotoxin (lipopolysaccharide, LPS) challenges. Breath was collected from ten healthy non-smoking subjects at eight time points before and after segmental and whole lu...
Trea, Fouzia Tichati, Lazhari Ouali, Kheireddine
Published in
Drug and chemical toxicology
The aim of the present study was to examine the possible protective effects of the aqueous extract of Thymus munbyanus (TMAE) against 2,4-dichlorophenoxyacetic acid (2,4-D)-induced oxidative stress and renal injury in the kidney of male albino rats. Furthermore, TMAE was assessed to determine the phenolic content. In vitro, antioxidant activities w...
Yang, Dong Huang, Wan-Yi Li, Yan-Qiao Chen, Shi-Yu Su, Si-Yu Gao, Yue Meng, Xian-Li Wang, Ping
Published in
Drug and chemical toxicology
Rhein is a key ingredient in many herbal remedies and is widely used. However, herbs containing rhein are frequently associated with poisoning incidents, especially in elderly subjects. Acute and subchronic toxicity of rhein in Kunming mice (KM) was investigated in this experiment. Acute toxicity tests showed a 40% lethality at a given rhein dose o...
Sayyed, Katia Hdayed, Ibrahim Tabcheh, Mohamad Abdel-Razzak, Ziad El-Bitar, Hoda
Published in
Drug and chemical toxicology
Iris x germanica L., which belongs to the Iridaceae family, has been reported in the literature for its antioxidant properties in acellular chemical-antioxidant assays. Chlorpromazine (CPZ) is an antipsychotic drug known to cause adverse reactions in humans. Oxidative stress is among the main mechanisms by which CPZ exerts its toxicity in animal ce...
Özakıncı, Osman Gökhan Gündüzöz, Meside Buyuksekerci, Murat Karataş, Mevlüt Balik, Ahmet Rifat Neselioglu, Salim Erel, Özcan
Published in
International journal of environmental health research
This study was designed to determine thiol-disulfide homeostasis as indices of oxidative stress in painters by using a novel and automated colorimetric measurement method. Male painters (n = 117) were separated into three groups according to duration of work; group 1 (
Valavi, Elham Zaeemi, Mahdieh Mohri, Mehrdad
Published in
Journal of animal physiology and animal nutrition
Early-life diseases in dairy animals are main causes of economic loss in livestock production. Oxidative stress (OS) and thyroid hormones are important inter-related components in the normal physiology of this critical period of life. However, limited information regarding their physiology in goat kids is available. This study was conducted to inve...
Folayan, Adeniyi Akani, Emmanuel Adebayo, Olayinka A Akanni, Olubukola O Owumi, Solomon E Tijani, Abiola S Adaramoye, Oluwatosin A
Published in
Drug and chemical toxicology
Garcinia kola seed is used to manage liver diseases in ethnomedicine. However, there is limited information on its role in Cisplatin (CIS)-induced toxicity. Here, we investigated the potential of hexane extract of Garcinia kola (HEGK) in lessening CIS-induced hepatorenal- and gene- toxicity. Male mice (22 ± 3 g) randomly assigned into groups (n = 5...
Chen, Zixuan Rasheed, Madiha Deng, Yulin
Published in
Brain pathology (Zurich, Switzerland)
Mitochondrial dysfunction is one of the crucial factors involved in PD's pathogenicity, which emerges from a combination of genetic and environmental factors. These factors cause differential molecular expression in neurons, such as varied transcriptional regulation of genes, elevated oxidative stress, α-synuclein aggregation and endogenous neuroto...
Galaup, Chantal Picard, Claude Couderc, François Gilard, Véronique Collin, Fabrice
Published in
The FEBS journal
Histopathological hallmarks of Alzheimer's disease (AD) are intracellular neurofibrillary tangles and extracellular formation of senile plaques composed of the aggregated amyloid-beta peptide along with metal ions (copper, iron or zinc). In addition, oxidative stress is considered as an important factor in the etiology of AD and a multitude of meta...
