Lee, Bohm Cho, Yongcheol
Published in
International journal of molecular sciences
Neurons are structurally unique and have dendrites and axons that are vulnerable to injury. Some neurons in the peripheral nervous system (PNS) can regenerate their axons after injuries. However, most neurons in the central nervous system (CNS) fail to do so, resulting in irreversible neurological disorders. To understand the mechanisms of axon reg...
Dua, Tarun K Joardar, Swarnalata Chakraborty, Pratik Bhowmick, Shovonlal Saha, Achintya De Feo, Vincenzo Dewanjee, Saikat
Published in
Molecules (Basel, Switzerland)
The present study evaluated the therapeutic potential of myricitrin (Myr), a glycosyloxyflavone extracted from Myrica esculenta bark, against diabetic nephropathy. Myr exhibited a significant hypoglycemic effect in high fat-fed and a single low-dose streptozotocin-induced type 2 diabetic (T2D) rats. Myr was found to improve glucose uptake by the sk...
Awada, Gil Jansen, Yanina Schwarze, Julia Katharina Tijtgat, Jens Hellinckx, Lennert Gondry, Odrade Vermeulen, Sim Warren, Sarah Schats, Kelly van Dam, Pieter-Jan
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Published in
Cancers
Pembrolizumab improves the survival of patients with advanced melanoma. A comprehensive analysis of baseline variables that predict the benefit of pembrolizumab monotherapy has not been conducted. Survival data of patients with advanced melanoma who were treated with pembrolizumab in a single university hospital were collected. A multivariate Cox r...
Miyasaka, Yuhei Komatsu, Shuichiro Abe, Takanori Kubo, Nobuteru Okano, Naoko Shibuya, Kei Shirai, Katsuyuki Kawamura, Hidemasa Saitoh, Jun-Ichi Ebara, Takeshi
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Published in
Cancers
Lung cancer is a leading cause of cancer-related deaths worldwide. Radiotherapy is an essential treatment modality for inoperable non-small cell lung cancer (NSCLC). Stereotactic body radiotherapy (SBRT) is the standard treatment for early-stage NSCLC because of its favorable local control (LC) compared to conventional radiotherapy. Carbon ion radi...
Nestares, Teresa Martín-Masot, Rafael Flor-Alemany, Marta Bonavita, Antonela Maldonado, José Aparicio, Virginia A
Published in
Nutrients
The current study was designed to assess the influence of consumption of ultra-processed (UPF) on oxidative/antioxidant balance and evoked inflammatory signaling in young patients with celiac disease (CD). The study included 85 children. The celiac group (n = 53) included children with CD with a long (>18 months, n = 17) or recent (
Froechlich, Guendalina Gentile, Chiara Infante, Luigia Caiazza, Carmen Pagano, Pasqualina Scatigna, Sarah Cotugno, Gabriella D'Alise, Anna Morena Lahm, Armin Scarselli, Elisa
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Published in
International journal of molecular sciences
HER2-based retargeted viruses are in advanced phases of preclinical development of breast cancer models. Mesothelin (MSLN) is a cell-surface tumor antigen expressed in different subtypes of breast and non-breast cancer. Its recent identification as a marker of some triple-negative breast tumors renders it an attractive target, presently investigate...
Delikhoon, Mahdieh Guzman, Marcelo I Nabizadeh, Ramin Norouzian Baghani, Abbas
Published in
International journal of environmental research and public health
The multiple modes of SARS-CoV-2 transmission including airborne, droplet, contact, and fecal-oral transmissions that cause coronavirus disease 2019 (COVID-19) contribute to a public threat to the lives of people worldwide. Herein, different databases are reviewed to evaluate modes of transmission of SARS-CoV-2 and study the effects of negative pre...
Ježek, Jan Cooper, Katrina F. Strich, Randy
Cancer is one of the world’s deadliest afflictions. Despite recent advances in diagnostic and surgical technologies, as well as improved treatments of some individual tumor types, there is currently no universal cure to prevent or impede the uncontrolled proliferation of malignant cells. Targeting tumors by inducing apoptosis is one of the pillars ...
Sawicki, Konrad Teodor Sala, Valentina Prever, Lorenzo Hirsch, Emilio Ardehali, Hossein Ghigo, Alessandra
Anthracyclines are the cornerstone of many chemotherapy regimens for a variety of cancers. Unfortunately, their use is limited by a cumulative dose-dependent cardiotoxicity. Despite more than five decades of research, the biological mechanisms underlying anthracycline cardiotoxicity are not completely understood. In this review, we discuss the inci...
Han, Eun-Jeong Lee, JungSuk Cho, Eunhee Kim, Hyejin
Published in
International journal of environmental research and public health
This study examined the socioeconomic costs of dementia based on the utilization of healthcare and long-term care services in South Korea. Using 2016 data from two national insurance databases and a survey study, persons with dementia were categorized into six groups based on healthcare and long-term care services used: long-term care insurance use...