Hirakawa, Akihiro Sato, Hiroyuki Hanazawa, Ryoichi Suzuki, Keisuke
Published in
Statistics in medicine
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by a gradual decline in cognitive function over a few decades. The Mini-Mental State Examination (MMSE) is a widely used measure for evaluating global cognitive functioning. Characterizing the longitudinal trajectory of the MMSE in the population of interest is important ...
Dubois, François Lafitte, Olivier
We consider in this contribution a simplified idealized one-dimensional coupled model for neutronics and thermo-hydraulics under the low Mach number approximation. We propose a numerical method treating globally the coupled problem for finding its unique solution. Simultaneously, we use incomplete elliptic integrals to represent analytically the ne...
Bhowmik, Purnendu Rajagopal, Sreenath Hmar, Rothangamawi Victoria Singh, Purnima Saxena, Pragya Amar, Prakruthi Thomas, Teby Ravishankar, Rajani Nagaraj, Savitha Katagihallimath, Nainesh
...
Published in
ACS synthetic biology
Using Escherichia coli as the representative biofilm former, we report here the development of an in silico model built by simulating events that transform a free-living bacterial entity into self-encased multicellular biofilms. Published literature on ∼300 genes associated with pathways involved in biofilm formation was curated, static maps were c...
deen, caleb
Can a replicase be found in the vast sequence space by random drift? We partially answer this question through a proof-of-concept study of the times of occurrence (hitting times) of some critical events in the origins of life for low-dimensional RNA sequences using a mathematical model and stochastic simulation studies from Python software. We para...
Tursunov, D. A. Sulaimanov, Z. M. Khalmatov, A. A.
Published in
Lobachevskii Journal of Mathematics
AbstractThe article investigates the two point boundary-value problem for a singularly perturbed linear in homogeneous ordinary differential equation of the second order on a segment with a turning point and interior layer. The aim of the study is to construct a uniform asymptotic expansion of the solution of the two point problem with an arbitrary...
Charles, Sandrine Ratier, Aude Lopes, Christelle
This paper gives the full analytical solution of the generic set of ordinary differential equations that define onecompartment toxicokinetic models. These models describe the uptake and elimination processes that occur within living organisms when exposed to chemical substances. The models solved in this paper consider living organisms as a unique ...
Karagöz, Zeynep Geuens, Thomas LaPointe, Vanessa L. S. van Griensven, Martijn Carlier, Aurélie
Published in
Frontiers in Bioengineering and Biotechnology
Vasilieva, Olga Cardona-Salgado, Daiver Dumont, Yves
Diaphorina citri or Asian citrus psyllids (ACP) are small insects that live on citrus trees and feed onyoung stems, sprouts, and leaves during all stages of development. This insect is also the major vectorof the most serious citrus plant disease known as Huanglongbing (HLB or Citrus Greening) that affectscitrus production in various parts of the w...
Korosteleva, D. M. Samsonov, A. A. Solov’ev, P. S. Solov’ev, S. I.
Published in
Lobachevskii Journal of Mathematics
AbstractThe differential eigenvalue problem governing eigenvibrations of an elastic bar with fixed first end and mechanical resonator attached to second end is investigated. This problem has an increasing sequence of positive simple eigenvalues with limit point at infinity. To the sequence of eigenvalues, there corresponds a complete orthonormal sy...
Karagöz, Zeynep Geuens, Thomas LaPointe, Vanessa L. S. van Griensven, Martijn Carlier, Aurélie
Published in
Frontiers in Bioengineering and Biotechnology
Integrin transmembrane proteins conduct mechanotransduction at the cell–extracellular matrix (ECM) interface. This process is central to cellular homeostasis and therefore is particularly important when designing instructive biomaterials and organoid culture systems. Previous studies suggest that fine-tuning the ECM composition and mechanical prope...