During the transition period, dairy cows experience a negative energy balance (NEB) caused by the high energy requirement for milk yield, while feed intake is limited. Severity of the NEB has been associated with an increased incidence of metabolic disorders and infectious diseases, inflammation, immunosuppression and oxidative stress. It is known ...
The fatty acid composition of our daily diet is considered a major determinant of long-term health risk and the development of disease. Several lines of evidence point toward a state of chronic ‘low-grade’ inflammation as an overarching process that is modulated by fatty acids and their different metabolites. Diets rich in omega-3 polyunsaturated f...
Published in Podosophia
Jicht is de meest voorkomende gewrichtsaandoening in Nederland waarbij veelal het MTP1-gewricht ontstoken is. Jicht kan op de lange termijn ernstige gewrichtsschade en veranderingen in de huid veroorzaken waardoor voetpijn, chronische wonden en/of standsafwijkingen ontstaan. Ook is het een risicofactor voor hart- en vaatziekten. Jicht is behandelba...
Published in JGZ Tijdschrift voor jeugdgezondheidszorg
Op een vaccinatieprikplaats kunnen vroege en latere reacties optreden. Vroege reacties (
Background Type 2 diabetes (T2D) and cardiovascular diseases (CVD) are important causes of morbidity and mortality worldwide. The metabolic syndrome (MetS) identifies people at elevated risk of T2D and CVD by its mutual risk factors, such as abdominal obesity, atherogenic dyslipidemia, raised blood pressure and impaired glucose tolerance. Improveme...
Background: The world faces a “double burden” of malnutrition; this is true especially in transition countries like Mexico. The co-existence of obesity and iron deficiency (ID) within a person has been clearly demonstrated in several studies but the mechanisms linking them remain largely unknown. Objectives: To investigate possible mechanisms that ...
Summary of main findings When adipose tissue is present in excessive amounts, as in obesity, it predisposes to a number of pathologies. Obesity is a complex, multifactorial condition as it influences many endogenous genetic, endocrine, and inflammatory pathways. Excess dietary intake is one of the important factors which are responsible for the inc...
Background Incidence of type 2 diabetes has rapidly increased during the last decades. It is a chronic disease caused by impaired insulin action and insulin secretion. Potentially, the majority of the new cases are due to changes in lifestyle, including unfavourable changes in diet. Lifestyle interventions promoting a healthy diet and physical acti...
Inflammatory processes are critical components of many illnesses, and dietary n-3 fatty acids have been shown to contribute to a reduction of the inflammatory status, both in in vivo and in vitro studies. The mechanisms underlying the modulation of inflammation are not completely understood, but it is clear that dietary n-3 fatty acids alter the ei...
