An Unsupervised Approach for Predicting Transporter-Mediated Drug-Metabolite Interactions
Organic anion transporter 1 (OAT1) and 3 (OAT3) are multi-specific renal drug transporters that facilitate the uptake and clearance of a wide range of endogenous and exogenous molecules. While they’ve been extensively studied for their clinical role in drug disposition and potential drug-drug interactions (DDIs), their physiological role in regulat...