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with nucleolar localization signal as keyword
Zhou, Jianwei Li, Juan Li, Haimin Zhang, Ying Dong, Weiren Jin, Yulan Yan, Yan Gu, Jinyan Zhou, Jiyong
Published in
Veterinary Research
The transport of circovirus capsid protein into nucleus is essential for viral replication in infected cell. However, the role of nucleolar shuttle proteins during porcine circovirus 3 capsid protein (PCV3 Cap) import is still not understood. Here, we report a previously unidentified nucleolar localization signal (NoLS) of PCV3 Cap, which hijacks t...
Zhou, Jianwei Dai, Yadong Lin, Cui Zhang, Ying Feng, Zixuan Dong, Weiren Jin, Yulan Yan, Yan Zhou, Jiyong Gu, Jinyan
...
Published in
Virulence
Entry of circovirus into the host cell nucleus is essential for viral replication during the early stage of infection. However, the mechanisms by which nucleolar shuttle proteins are used during viral replication is still not well understood. Here, we report a previously unidentified nucleolar localization signal in circovirus capsid protein (Cap),...
Sleiman, Sophie Dragon, Francois
Published in
Cells
Ribosome biogenesis is one of the most energy demanding processes in the cell. In eukaryotes, the main steps of this process occur in the nucleolus and include pre-ribosomal RNA (pre-rRNA) processing, post-transcriptional modifications, and assembly of many non-ribosomal factors and ribosomal proteins in order to form mature and functional ribosome...
Kurnaeva, Margarita Sheval, Eugene Musinova, Yana Vassetzky, Yegor
International audience
Hoellerich, Elisa Dunagan, Christie Maring, Daniel C. Wong, Yun-Lan Shouldice, Daniel Stripe, Jennifer Kline, Tayah Albert, Thomas J. Milhon, Jon L.
Published in
Molecular & Biochemical Parasitology
SmMAK16 from the trematode Schistosoma mansoni is a protein that is known to localize in the nucleolus. Recent findings show that SmMAK16 is involved in 60S ribosomal subunit synthesis. Although the SmMAK16 protein contains putative nuclear localization signals (NLS), little is known about their precise function, redundancy or regulation. The goal ...
Kiran, Shashi Chatterjee, Nirupama Singh, Sapna Kaul, Sunil C Wadhwa, Renu Ramakrishna, Gayatri
Published in
The FEBS journal
Sirtuins belong to a class of NAD-dependent deacetylases, and include seven distinct isoforms, of which SIRT7 is the least studied member. In the present study, the subcellular expression of SIRT7 in primary fibroblasts undergoing senescence was evaluated by immunocytochemistry and immunoblot assay. Expression of nucleolar SIRT7 in young fibroblast...
