stephanie, filia friend tambunan, usman sumo kuczera, krzysztof siahaan, teruna j.
Background and Objectives: A novel antitubercular cyclic peptide, Cyclo(1,6)-Ac-CLYHFC-NH2, was designed to bind at the rifampicin (RIF) binding site on the RNA polymerase (RNAP) of Mycobacterium tuberculosis (MTB). This peptide inhibits RNA elongation in the MTB transcription initiation assay in the nanomolar range, which can halt the MTB transcri...
shelyapina, marina g.
Unique structural and chemical properties, such as ion exchange, developed inner surface, etc., as well as the wide possibilities and flexibility of regulating these properties, cause a keen interest in zeolites. They are widely used in industry as molecular sieves, ion exchangers and catalysts. Current trends in the development of zeolite-based ca...
Lourette, Sean Jarmola, Andrey Chathanathil, Jabir Carrasco, Sebastián C Budker, Dmitry Malinovskaya, Svetlana A Birdwell, A Glen Ivanov, Tony G Malinovsky, Vladimir S
Published in
Quantum Science and Technology
We report the first experimental demonstration of stimulated Raman adiabatic passage (STIRAP) in nuclear-spin transitions of 14N within nitrogen-vacancy color centers in diamond. It is shown that the STIRAP technique suppresses the occupation of the intermediate state, which is a crucial factor for improvements in quantum sensing technology. Buildi...
Hwang, Junik Park, Seonghoon Hyun Kim, Beom Kim, Junghyun Park, Je-Geun Baek, Seung-Ho
Published in
Journal of Physics: Condensed Matter
Cross-coupling among the fundamental degrees of freedom in solids has been a long-standing problem in condensed matter physics. Despite its progress using predominantly three-dimensional materials, how the same physics plays out for two-dimensional materials is unknown. Here, we show that using 31P nuclear magnetic resonance (NMR), the van der Waal...
zhang, zhicai wang, feng ling, xu
Ginkgo biloba extract (EGB) has been approved by the Food and Drug Administration in the United States for clinical studies on memory disorders. Ginkgolide B (GB) is the major terpene lactone component of EGB and is a specific and potent antagonist of platelet-activating factor (PAF). In a previous study, we reported the medium composition for the ...
mortensen, jonas ellegaard andreassen, trygve olsen, dorte aalund vestergaard, karsten madsen, jonna skov kristensen, søren risom pedersen, shona
Identifying biomarkers for Alzheimer’s disease (AD) is crucial, due to its complex pathology, which involves dysfunction in lipid transport, contributing to neuroinflammation, synaptic loss, and impaired amyloid-β clearance. Nuclear magnetic resonance (NMR) is able to quantify and stratify lipoproteins. The study investigated lipoproteins in blood ...
yin, hu zhong, gaorun liu, jiangbin yanjun, wu
Surfactant flooding is a pivotal technique for enhancing oil recovery efficiency. The Chang 8 member of the Yanchang Formation in the Ordos Basin exemplifies a quintessential tight oil reservoir. Specifically, 47.9% of wells yield less than 0.1 t/d, 27.0% produce between 0.1 and 0.2 t/d, and 18.8% generate outputs ranging from 0.2 to 0.3 t/d, while...
Stern, Quentin Verhaeghe, Guillaume El Daraï, Théo Montarnal, Damien Huu Le, Nghia Veyre, Laurent Thieuleux, Chloé Bocquelet, Charlotte Cala, Olivier Jannin, Sami
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Abstract The low sensitivity of liquid‐state nuclear magnetic resonance (NMR) can be overcome by hyperpolarizing nuclear spins by dissolution dynamic nuclear polarization (dDNP). It consists of transferring the near‐unity polarization of unpaired electron spins of stable radicals to the nuclear spins of interest at liquid helium temperatures, below...
kuhn, stefan de jesus, rômulo pereira borges, ricardo moreira
This review explores the current applications of artificial intelligence (AI) in nuclear magnetic resonance (NMR) spectroscopy, with a particular emphasis on small molecule chemistry. Applications of AI techniques, especially machine learning (ML) and deep learning (DL) in the areas of shift prediction, spectral simulations, spectral processing, st...
Daiana, Ibarretxe Dídac, Llop Cèlia, Rodríguez-Borjabad Natalia, Andreychuk Núria, Plana Roberto, Scicali Ana, González-Lleó Núria, Amigó Josefa, Girona Lluís, Masana
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Published in
The Journal of clinical endocrinology and metabolism
The familial hypercholesterolemia (FH) diagnosis is based on clinical and genetic criteria. A relevant proportion of FH patients fulfilling the criteria for definite FH have negative genetic testing. Increasing the identification of true genetic-based FH is a clinical challenge. Deepening the analysis of lipoprotein alterations could help increase ...