Uvod: Okužba z virusom herpes simpleks (HSV) je najpogostejša spolno prenosljiva bolezen, razširjena po vsem svetu, s katero je okuženih več žensk kot moških. Poznana sta dva podtipa virusa, HSV-1 in HSV-2. Prvi primarno povzroča orofacialni herpes, drugi pa genitalni herpes. Okužba se lahko pojavi kadarkoli v življenju, posebej pa je ogrožajoča te...
Published in Antibiotics
(1) Background: Empirical antibiotics for suspected neonatal early-onset sepsis are often prolonged administered, even in the absence of clinical signs of infection, while awaiting the blood cultures results. The C-reactive protein is widely used to guide antibiotic therapy, although its increase in the first hours of life is not always evidence of...
Published in International Journal of Molecular Sciences
Neonatal hypoxic-ischemic (HI) brain injury is one of the major drawbacks of mortality and causes significant short/long-term neurological dysfunction in newborn infants worldwide. To date, due to multifunctional complex mechanisms of brain injury, there is no well-established effective strategy to completely provide neuroprotection. Although thera...
Published in Cureus
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in newborns is extremely rare, and there is a scarcity of research pertaining to epidemiology, clinical presentation, transmission, and prognosis in this population. We present five newborns who tested positive while colocating with their SARS-CoV-2 positive mothers fr...
Published in International Journal of Molecular Sciences
Bilirubin toxicity to the central nervous system (CNS) is responsible for severe and permanent neurologic damage, resulting in hearing loss, cognitive, and movement impairment. Timely and effective management of severe neonatal hyperbilirubinemia by phototherapy or exchange transfusion is crucial for avoiding permanent neurological consequences, bu...
Published in Clinical EEG and neuroscience
In 2 previous studies, we have shown the ability of special machine learning systems applied to standard EEG data in distinguishing children with autism spectrum disorder (ASD) from non-ASD children with an overall accuracy rate of 100% and 98.4%, respectively. Since the equipment routinely available in neonatology units employ few derivations, we ...
Published in Pediatric Health, Medicine and Therapeutics
Background Macrosomia is defined as a birth weight of newborns ≥4000 grams irrespective of gestational age. It is becoming a burning public health issue in most developing countries and contributes to maternal and newborn complications. Though macrosomia has been increasing in Ethiopia, evidence about its magnitude and associated factors is limited...
Published in CNS & neurological disorders drug targets
While phenobarbital (PB) is commonly used for the management of seizures in newborns and pediat-rics, its administration may accompany with acute poisoning. We aimed to review the literature to find out the frequency of PB poisonings in newborns and children with seizures. Literature search was performed by two independent reviewers to find relevan...
In Central-Africa, neonatal infections, asphyxia and prematurity are main reasons for admission to the neonatal intensive care unit and major determinants of newborn survival. Also, the outcome of newborns with congenital anomalies is expected to be poor, due to a lack of state-of-the art care. We conducted a study of 102 newborns recruited in the ...
