Limon, Utku Sezgin Akcay, Betül Ilkay
Published in
European journal of ophthalmology
To evaluate the add-on effect of simultaneous intravitreal dexamethasone implant to bevacizumab for treatment of neovascular serous retinal pigment epithelial detachment (PED) secondary to neovascular age-related macular degeneration (nAMD). A 72-year-old male patient was previously treated with intravitreal bevacizumab and aflibercept for neovascu...
Song, Xian Xu, Qian Li, Haiming Fan, Qian Zheng, Yefeng Zhang, Qiang Chu, Chunyan Zhang, Zhicheng Yuan, Chenglang Ning, Munan
...
Published in
Frontiers in Neuroscience
Purpose Using deep learning (DL)-based technique, we identify risk factors and create a prediction model for refractory neovascular age-related macular degeneration (nAMD) characterized by persistent disease activity (PDA) in spectral domain optical coherence tomography (SD-OCT) images. Materials and methods A total of 671 typical B-scans were coll...
Zhang, Xinyuan Qiu, Bingjie Gong, Zhizhong Chen, Xiaosi Wang, Yanhong Nie, Yao
Published in
Frontiers in Endocrinology
Lipid dyshomeostasis has been implicated in the pathogenesis of various retinal and choroidal vascular diseases. This study aims to investigate whether apolipoprotein (apo) mediated differential regulation of lipid metabolism contributes to the phenotypes of polypoidal choroidal vasculopathy (PCV) and neovascular age-related macular degeneration (n...
Altinisik, Muhammed Kurt, Emin Sonmezer, Pinar Kayikcioglu, Ozcan Ilker, Suleyman Sami
Published in
European journal of ophthalmology
This study aimed to compare type 1 choroidal neovascularization (CNV) characteristics in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA). Treatment naive 23 eyes of 23 patients with PNV and 24 eyes of 24 patients with nAMD were evaluated. The ...
Jia, Huixun Lu, Bing Yuan, Yuanzhi Yuan, Fei Li, Lei Song, Yanping Rong, Ao Zhou, Minwen Wang, Fenghua Sun, Xiaodong
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Published in
Frontiers in Medicine
Purpose To compare the efficacy and safety of conbercept using a treat-and-extend (T&E) regimen vs. a pro re nata (PRN) regimen in Chinese patients with neovascular age-related macular degeneration (nAMD). Methods This was a randomized, multicenter, non-inferiority study. After an initial loading phase of three consecutive monthly intravitreal inje...
Ehlers, Justis P. Patel, Nikhil Kaiser, Peter K. Heier, Jeffrey S. Brown, David M. Meng, Xiangyi Reese, Jamie Lunasco, Leina Le, Thuy K. Hu, Ming
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Published in
Investigative Ophthalmology & Visual Science
Purpose To evaluate the association of fluid volatility with ellipsoid zone (EZ) integrity and subretinal hyperreflective material (SHRM) volume during anti–vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration (nAMD). Methods This study was a post hoc analysis of the OSPREY study. Retinal volatility was ...
Thier, Anne Breuning, Martina Wolfram, Christian Zeitz, Oliver Holmberg, Christine
Published in
BMJ open
In order to better understand the continued barriers to the provision of vascular endothelial inhibitor therapy, this study aims to investigate patients' experiences with neovascular age-related macular degeneration (nvAMD) in Germany during the injection process and how they deal with it. This analysis is part of the qualitative arm of a wider mix...
qiu;, bingjie
The objective of this study was to characterize the choroidal morphology and vasculature in pachychoroid diseases (PCD). A total of 49 eyes with polypoidal choroidal vasculopathy (PCV), 43 eyes with neovascular age-related macular degeneration (nAMD), and 50 eyes with central serous chorioretinopathy (CSC), along with 80 healthy eyes, were enrolled...
Vogt, Denise Deiters, Viktoria Herold, Tina R Guenther, Stefanie R Kortuem, Karsten U Priglinger, Siegfried G Wolf, Armin Schumann, Ricarda G
Published in
Current eye research
To report on long-term real-life outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy in neovascular age-related macular degeneration (nAMD) with optimal patient adherence. For this retrospective monocenter study, we identified 3217 eyes of 2793 patients that received a minimum of three intravitreal anti-VEGF injections for nAMD ...
Schroeder, Marion Westborg, Inger Fluur, Caroline Olsen, Rasmus Lövestam-Adrian, Monica
Published in
Acta ophthalmologica
To analyse and compare the number and interval of anti-vascular endothelial growth factor (anti-VEGF) injections in neovascular age-related macular degeneration (nAMD), as well as the visual development in patients followed up for one to three years in clinical practice and during different index periods. This observational study included treatment...
