Kato, Yutaka Oguchi, Yasuharu Omori, Tomoko Shintake, Hiroaki Tomita, Ryutaro Kasai, Akihito Ogasawara, Masashi Sugano, Yukinori Itagaki, Kanako Ojima, Akira
...
Published in
Investigative Ophthalmology & Visual Science
Purpose To investigate the characteristics of complement activation products and angiogenic cytokines in the aqueous humor in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD). Methods This was a prospective, comparative, observational study. All patients with choroidal neovascularization were clas...
Chen, Qian Jiang, Nan Zhang, Yuhan Ye, Sihao Liang, Xu Wang, Xin Lin, Xiang Zong, Rongrong Chen, Haoyu Liu, Zuguo
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Published in
Frontiers in Pharmacology
Subretinal fibrosis is a common pathological change that causes vision loss in neovascular age-related macular degeneration (nAMD). Treatment modalities for subretinal fibrosis are limited. In the present study, the effects of fenofibrate, a specific peroxisome proliferator–activated receptor alpha agonist, on subretinal fibrosis of nAMD were teste...
Stepanov, Alexandr Nemcansky, Jan Veith, Miroslav Manethova, Katerina Stredova, Marketa Pencak, Martin Tarkova, Anna Studnicka, Jan
Published in
European journal of ophthalmology
To present the results of a 2-year therapy with aflibercept in real-life practice in a mixed regimen in patients with a neovascular form of age-related macular degeneration (nAMD) and to evaluate the treatment response of various types of choroidal neovascular membranes (CNV) - occult (Type 1), classic (Type 2) and minimally classic (Type 4). This ...
López Gálvez, María Isabel Arias Barquet, Lluís S Figueroa, Marta García-Layana, Alfredo Ruiz Moreno, José M
Published in
Acta ophthalmologica
To assess the noninferiority of the treat-and-extend (T&E) and fixed bimonthly regimens of 0.5 mg intravitreal ranibizumab as compared with the pro re nata (PRN) in naïve patients with neovascular age-related macular degeneration (nAMD). Phase IV, randomized, 12-month, multicentre trial. Patients aged ≥50 years with nAMD and visual impairment [best...
Dharamdasani Detaram, Harshil Liew, Gerald Russell, Joanna Vu, Kim Van Burlutsky, George Mitchell, Paul Gopinath, Bamini
Published in
Acta ophthalmologica
To assess whether dietary intake of antioxidants, fruits, vegetables and fish is associated with 12-month treatment outcomes in neovascular age-related macular degeneration (nAMD) patients. A total of 547 participants were diagnosed with nAMD at baseline, of whom 494 were followed up after 12 months of antivascular endothelial growth factor therapy...
Barış, Mine Esen Menteş, Jale Afrashi, Filiz Nalçaçı, Serhad Akkın, Cezmi
Published in
Turkish Journal of Ophthalmology
Objectives: This study aimed to determine the incidence of poor response to intravitreal (IV) anti-VEGF treatment in neovascular age-related macular degeneration (nvAMD) and to define subgroups of poor responders. Materials and Methods: A total of 235 treatment-naive eyes of 202 patients completed this prospective study. Patients younger than 50 ye...
Branisteanu, Daniel Constantin Branisteanu, Daciana Elena Feraru, Crenguta Ioana Branisteanu, Catalina Ioana Moraru, Andreea Zemba, Mihail Balta, Florian
Published in
Experimental and Therapeutic Medicine
Neovascular age-related macular degeneration (neovascular ARMD) represents only 10% of ARMD cases but is responsible, if untreated, for quick and severe central vision loss due to major macular changes. The presence of choroidal neovascularization (CNV) in one eye is associated with an approximately 10% risk of CNV development in the fellow eye eac...
Faatz, Henrik Rothaus, Kai Ziegler, Martin Book, Marius Lommatzsch, Claudia Spital, Georg Gutfleisch, Matthias Pauleikhoff, Daniel Lommatzsch, Albrecht
Published in
Clinical Ophthalmology (Auckland, N.Z.)
Purpose The aim of this study was to ascertain and quantify the differences between swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA) imaging of macular neovascularizations (MNV) in neovascular age-related macular degeneration (nAMD). Patients and Methods SD-OCTA (RTVue Avanti) and SS-OCTA (PLEX® Elite 9000)...
Benisek, Daniel A. Manzitti, Julio Scorsetti, Daniel Rousselot Ascarza, Andres M. Ascarza, Amalia A. Gomez Rancaño, Diego Quercia, Romina Ramirez Gismondi, Matias Carpio Total, Mateo A. Scorsetti, María L.
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Published in
Experimental and Therapeutic Medicine
The present study was an open-label, prospective, uncontrolled and multicenter clinical trial to investigate the safety and effectiveness of bevacizumab (Lumiere®) administered by the intravitreal route for the treatment of neovascular age-related macular degeneration (nAMD). A total of 22 patients without previous treatment with anti-vascular endo...
Bhagat, Davis Kirby, Breanne Bhatt, Harit Jager, Rama George, Meena Sheth, Veeral
Published in
Clinical Ophthalmology (Auckland, N.Z.)
Purpose To evaluate treatment-related preferences among patients receiving intravitreal anti-vascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (nAMD) or diabetic macular edema (DME). Patients and Methods We conducted a prospective survey of patients with nAMD or DME treated at one of three US-based r...
