Non-ketotic hyperglycinaemia: a frequent, but poorly diagnosed and managed genetic disorder in Tunisia.
Published in Archives of disease in childhood
Return of Spontaneous Circulation Depends on Cardiac Rhythm During Neonatal Cardiac Arrest in Asphyxiated Newborn Animal...
Published in Frontiers in Pediatrics
Objective: Pulseless electrical activity (PEA) occurs in asphyxiated newborn piglets and infants. We aimed to examine whether different cardiac rhythms (asystole, bradycardia, PEA) affects the resuscitation outcomes during continuous chest compressions (CC) during sustained inflations (CC+SI). Design: This study is a secondary analysis of four prev...
How to do no harm: empowering local leaders to make care safer in low-resource settings.
Published in Archives of disease in childhood
In a companion paper, we showed how local hospital leaders could assess systems and identify key safety concerns and targets for system improvement. In the present paper, we consider how these leaders might implement practical, low-cost interventions to improve safety. Our focus is on making immediate safety improvements both to directly improve pa...
Cardiac or respiratory cause of hypoxia in a newborn.
Published in Archives of disease in childhood. Education and practice edition
Relationship between obesity and lower rates of breast feeding initiation in regional Victoria, Australia: an 8-year ret...
Published in BMJ Open
Objectives Using routinely collected hospital data, this study explored secular trends over time in breast feeding initiation in a large Australian sample. The association between obesity and not breast feeding was investigated utilising a generalised estimating equations logistic regression that adjusted for sociodemographics, antenatal, intrapart...
Risks associated with the evolution in the compounding process of parenteral nutrition solutions: use of the “FMECA” met...
Published in Pharmaceutical Technology in Hospital Pharmacy
ObjectivesAn audit of the practices of our compounding unit was performed in 2016: areas of improvement were proposed, such as the automatization of our process. An automated compounder was acquired (MediMixmulti® MF4120R). The aim of the study was to anticipate the risks of the new process, in order to improve its security and to support the profe...
Neonatal mortality and leading causes of deaths: a descriptive study in China, 2014–2018
...Published in BMJ Open
Objective The present study estimated the national and urban–rural levels and causes of neonatal deaths in China annually between 2014 and 2018 to provide data support for the further end of preventable neonatal deaths for China and other low-income and middle-income countries. Methods The study was based on data from the National Maternal and Chil...
Machine-Learning vs. Expert-Opinion Driven Logistic Regression Modelling for Predicting 30-Day Unplanned Rehospitalisati...
Published in Frontiers in Pediatrics
Introduction: Preterm babies are a vulnerable population that experience significant short and long-term morbidity. Rehospitalisations constitute an important, potentially modifiable adverse event in this population. Improving the ability of clinicians to identify those patients at the greatest risk of rehospitalisation has the potential to improve...
Problem solving in clinical practice: the sick infant with low sodium and high potassium.
Published in Archives of disease in childhood. Education and practice edition
Many paediatricians will be faced with a sick infant who on investigation is found to have hyponatraemia and hyperkalaemia at some time in their career. The focus of initial management includes the treatment of potentially life-threatening hyperkalaemia with concurrent investigation aiming to elucidate whether the underlying cause reflects a primar...
Achondroplasia Foramen Magnum Score: screening infants for stenosis.
Published in Archives of disease in childhood
Achondroplasia is associated with foramen magnum stenosis (FMS) and significant risk of morbidity and sudden death in infants. A sensitive and reliable method of detecting infants who require decompressive surgery is required. This study aims to describe the incidence and severity of FMS in an unselected, sequential series of infants using a novel ...
