hassan, muhammad aamir noor, sadaf park, jungmi nabawy, ahmed dedhiya, maitri patel, robin rotello, vincent m.
Fungal infections represent a significant global health challenge. Candida albicans is a particularly widespread pathogen, with both molecular and biofilm-based mechanisms making it resistant to or tolerant of available antifungal drugs. This study reports a combination therapy, active against C. albicans, utilizing terbinafine and essential oils i...
yan, yue wei, changhe liu, xin zhao, xin zhao, shanmei tong, shuai ren, guoyou wei, qin
The volatility, instability, and water insolubility of Camphora longepaniculata essential oil (CLEO) limit its practical applications in the food, pharmaceutical, and cosmetics industries. CLEO nanoemulsions (CLNEs) were formulated and characterized to overcome the aforementioned issues. The volatile compounds of CLEO were identified by gas chromat...
katsimichas, alexandros katsouli, maria spantidos, nikolaos giannakourou, maria c. taoukis, petros
Auxenochlorella pyrenoidosa is a microalga that stands out due to its high protein content. The objective of this work was to study the effect of high-pressure homogenization (HPH) on the recovery of proteins from A. pyrenoidosa and their application as functional emulsifiers. Untreated and HPH-treated (400–800 bar, 1 and 4 passes) aqueous cellular...
bhangde, shashank fresnay-murray, stephanie garretson, tyler ashraf, asma o’hagan, derek t. amiji, mansoor m. lodaya, rushit n.
Background: Adjuvants play a crucial role in improving the immunogenicity of various antigens in vaccines. Squalene-in-water emulsions are clinically established vaccine adjuvants that improve immune responses, particularly during a pandemic. Current manufacturing processes for these emulsion adjuvants include microfluidizers and homogenizers and t...
Zhang, Junkai Wang, Xilong Li, Pengliang Gao, Yanling Wang, Ruiyun Li, Shuaihua Yi, Kaifang Cui, Xiaodie Hu, Gongzheng Zhai, Yajun
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Published in
Frontiers in Veterinary Science
Colistin (COL) is regarded as a last-resort treatment for infections by multidrug-resistant (MDR) Gram-negative bacteria. The emergence of colistin-resistant Enterobacterales poses a significant global public health concern. Our study discovered that niclosamide (NIC) reverses COL resistance in Salmonella via a checkerboard assay. However, poor sol...
jacob, shery kather, fathima sheik s. boddu, sai h. shah, jigar nair, anroop b.
Nanoemulsions (NEs) are submicron-sized heterogeneous biphasic liquid systems stabilized by surfactants. They are physically transparent or translucent, optically isotropic, and kinetically stable, with droplet sizes ranging from 20 to 500 nm. Their unique properties, such as high surface area, small droplet size, enhanced bioavailability, excellen...
Saleh, Mohamed N. Salam, Mohamed Abdelbaset Çapanoğlu, Esra
This study aimed to improve the dispersibility of phenolic compounds from black rice bran through the encapsulation process within nanoemulsion. The study focused on assessing the stability of the nanoemulsions, which were prepared using a combination of surfactants with distinct hydrophilic–lipophilic balance (HLB) values and sunflower oil under d...
martín, félix guirao, pedro pascual-villalobos, maría jesús
Myzus persicae (Sulzer) (Hemiptera: Aphididae) is one of the most important aphid crop pests, due to its direct damage and its ability to transmit viral diseases in crops. The objective is to test whether spraying nanoemulsions of botanical products repels winged individuals of M. persicae in a bioassay in culture chambers. The bioactive volatiles ...
Xie, Chen Dong, Jing-Zhe Lu, Bing-Shuai Yan, Peng-Yao Zhao, Yun-Shan Ding, Xin-Yue Lv, Cheng-En Zheng, Xu
Published in
Frontiers in Pharmacology
The main bioactive components of agarwood, derived from Aquilaria sinensis, include sesquiterpenes, 2-(2-phenethyl) chromone derivatives, aromatic compounds, and fatty acids, which typically exert anti-inflammatory, antioxidant, immune-modulating, hypoglycemic, and antitumor pharmacological effects in the form of essential oils. Agarwood tree leave...
giordano, alessandra provenza, anna chiara reverchon, giorgio baldino, lucia reverchon, ernesto
Theranostics is a growing field that matches diagnostics and therapeutics. In this approach, drugs and techniques are uniquely coupled to diagnose and treat medical conditions synergically or sequentially. By integrating diagnostic and treatment functions in a single platform, the aim of theranostics is to improve precision medicine by tailoring tr...
