Srinivas, Sujatha Berger, Martine Brinkhoff, Thorsten Niggemann, Jutta
Published in
Frontiers in Microbiology
Microbial interactions shape ecosystem diversity and chemistry through production and exchange of organic compounds, but the impact of regulatory mechanisms on production and release of these exometabolites is largely unknown. We studied the extent and nature of impact of two signaling molecules, tropodithietic acid (TDA) and the quorum sensing mol...
nigg;, martha
The Ascomycete Ophiostoma novo-ulmi threatens elm populations worldwide. The molecular mechanisms underlying its pathogenicity and virulence are still largely uncharacterized. As part of a collaborative study of the O. novo-ulmi-elm interactome, we analyzed the O. novo-ulmi ssp. americana transcriptomes obtained by deep sequencing of messenger RNAs...
de la luz, maría
Agricultural biodiversity includes many species that have biological variants (natives, ecotypes, races, morphotypes). Their use is restricted to local areas because they do not fulfill the commercial requirements; however, it is well documented that these species are a source of metabolites, proteins, enzymes, and genes. Rescuing and harnessing th...
Yang, Tianyou Li, Linbo Wang, Baoshi Tian, Jing Shi, Fanghao Zhang, Shishuang Wu, Zhongqi
Published in
Frontiers in Microbiology
The highly effective phosphate-solubilizing microorganisms are significant for making full use of the potential phosphorus resources in the soil and alleviating the shortage of phosphorus resources. In this study, a phosphate-solubilizing fungus was isolated from wheat and cotton rhizosphere soils in the lower reaches of the Yellow River in China a...
Dehong, Xu Wenmei, Wu Siqin, Hong Peng, Zeng Xianchun, Wang Xiongzhi, Zeng
Published in
Channels
JZTX-V is a toxin isolated from the venom of the Chinese spider Chilobrachys jingzhao . Previous studies had shown that JZTX-V could inhibit the transient outward potassium current of Kv4.2 and Kv4.3 expressed in Xenopus oocytes but had no effects on Kv1.2–1.4. However, the underlying action mechanism of JZTX-V on Kv4.3 remains unclear. In our stud...
Tancer, Robert J. Wang, Yina Pawar, Siddhi Xue, Chaoyang Wiedman, Gregory R.
Published in
Microbiology Spectrum
Cryptococcus neoformans is a major fungal pathogen that often causes life-threatening meningitis in immunocompromised populations. This yeast pathogen is highly resistant to the echinocandin drug caspofungin. Previous studies showed that Cryptococcus lipid translocase (flippase) is required for the caspofungin resistance of that fungus. Mutants wit...
Dash, Manoranjan Somvanshi, Vishal Singh Godwin, Jeffrey Budhwar, Roli Sreevathsa, Rohini Rao, Uma
Published in
Frontiers in Plant Science
Rice (Oryza sativa) production is seriously affected by the root-knot nematode Meloidogyne graminicola, which has emerged as a menace in upland and irrigated rice cultivation systems. Previously, activation tagging in rice was utilized to identify candidate gene(s) conferring resistance against M. graminicola. T-DNA insertional mutants were develop...
Liang, Miaomiao Zhang, Fan Xu, Jiaxin Wang, Xiaoning Wu, Ruibo Xue, Zheyong
Published in
Proceedings of the National Academy of Sciences of the United States of America
SignificanceHopanoids are a group of biologically important triterpene scaffolds found in nature, but the discovery of hopane-type triterpene synthases in plants has not been reported. We discovered two types of triterpene synthases synthesizing hopanoid skeletons from monocot and dicot plants and elucidated a mechanism involving the deprotonation ...
Boro, Priyanka Sultana, Asma Mandal, Kajal Chattopadhyay, Sharmila
Published in
Journal of plant physiology
Glutathione (GSH) plays a fundamental role in plant defense. Recent reports showed that enhanced GSH content activates mitogen-activated protein kinases (MPKs). However, the molecular mechanism behind this GSH-mediated MPKs expression during environmental challenges is unexplored. Here, we found that under control and combined abiotic stress-treate...
hai, trung
Alzheimer’s disease displays aggregates of the amyloid-beta (Aβ) peptide in the brain, and there is increasing evidence that cholesterol may contribute to the pathogenesis of the disease. Though many experimental and theoretical studies have focused on the interactions of Aβ oligomers with membrane models containing cholesterol, an understanding of...
