Linked Mutations at Adjacent Nucleotides Have Shaped Human Population Differentiation and Protein Evolution.
Published in Genome biology and evolution
Despite the fundamental importance of single nucleotide polymorphisms (SNPs) to human evolution, there are still large gaps in our understanding of the forces that shape their distribution across the genome. SNPs have been shown to not be distributed evenly, with directly adjacent SNPs found unusually frequently. Why this is the case is unclear. We...