Jiang, Peifang Ling, Yinjie Zhu, Tao Luo, Xiaoying Tao, Yilin Meng, Feilong Cheng, Weixin Ji, Yanchun
Published in
Bioscience reports
To conduct the clinical, genetic and molecular characterization of 494 Han Chinese subjects with Tic disorders (TD). In this study, we performed the mutational analysis of 22 mitochondrial tRNA genes in a large cohort of 494 Han Chinese subjects with TD via Sanger sequencing. These variants were then assessed for their pathogenic potential via phyl...
Zurita, Antonio García-Sánchez, Ángela María Cutillas, Cristina
Published in
Bulletin of entomological research
The family Ctenophthalmidae (Order Siphonaptera) has been considered as a 'catchall' for a wide range of divergent taxa showing a paraphyletic origin. In turn, Ctenophthalmus sp. (Ctenophthalmidae) includes 300 valid described taxa. Within this genus, males are easily distinguishable basing on the size, shape, and chaetotaxy of their genitalia; how...
Kuscu, Cem Kuscu, Canan Bajwa, Amandeep Eason, James D Maluf, Daniel Mas, Valeria R
Published in
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
In transplantation, the ever-increasing number of an organ's demand and long-term graft dysfunction constitute some of the major problems. Therefore, alternative solutions to increase the quantity and quality of the organ supply for transplantation are desired. On this subject, revolutionary Clustered Regularly Interspaced Short Palindromic Repeats...
Tian, Jianbo Zhu, Ying Rao, Meilin Cai, Yimin Lu, Zequn Zou, Danyi Peng, Xiating Ying, Pingting Zhang, Ming Niu, Siyuan
...
Published in
Gut
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. Thus far, most drugs have failed to significantly improve patient survival. N6-methyladenosine (m6A) plays an important role in the progression of PDAC, but its aberrant regulation driven by germline variants in human diseases remains unclear. We first performed an...
Hunnestad, Annie Vera Vogel, Anne Ilse Maria Armstrong, Evelyn Digernes, Maria Guadalupe Ardelan, Murat Van Hohmann-Marriott, Martin Frank
Published in
Microorganisms
Iron is an essential, yet scarce, nutrient in marine environments. Phytoplankton, and especially cyanobacteria, have developed a wide range of mechanisms to acquire iron and maintain their iron-rich photosynthetic machinery. Iron limitation studies often utilize either oceanographic methods to understand large scale processes, or laboratory-based, ...
Ilie, Ovidiu-Dumitru Ciobica, Alin Riga, Sorin Dhunna, Nitasha McKenna, Jack Mavroudis, Ioannis Doroftei, Bogdan Ciobanu, Adela-Magdalena Riga, Dan
Published in
Medicina (Kaunas, Lithuania)
Intra-lysosomal accumulation of the autofluorescent "residue" known as lipofuscin, which is found within postmitotic cells, remains controversial. Although it was considered a harmless hallmark of aging, its presence is detrimental as it continually accumulates. The latest evidence highlighted that lipofuscin strongly correlates with the excessive ...
Roufosse, Candice Drachenberg, Cinthia Renaudin, Karine Willicombe, Michelle Toulza, Frederic Dominy, Kathy McLean, Adam Simmonds, Naomi de Kort, Hanneke Cantarovitch, Diego
...
Published in
Clinical transplantation
Pancreas transplant longevity is limited by immune rejection, which is diagnosed by graft biopsy using the Banff Classification. The histological criteria for antibody-mediated rejection (AMR) are poorly reproducible and inconsistently associated with outcome. We hypothesized that a 34-gene set associated with antibody-mediated rejection in other s...
Marinho, Feliciana Lage Zauli, Danielle
Published in
Sexually transmitted infections
Cruz-Gil, Silvia Fernández, Lara P. Sánchez-Martínez, Ruth Gómez de Cedrón, Marta Ramírez de Molina, Ana
Published in
Cancers
Simple Summary Reprogramming of energy metabolism is an emerging hallmark of cancer development. Progression in a tumor cell requires new biogenesis of fatty acids (FA) for membrane synthesis, as signaling molecules or as energy input. Here, we provide a review of fatty acid metabolism misbalance from a cancer perspective (lipids’ storage formation...
Yao, Xiaodan Ajani, Jaffer A. Song, Shumei
Published in
Translational Gastroenterology and Hepatology
Peritoneal metastases occur in 55–60% of patients with gastric cancer (GC) and are associated with a 2% 5-year overall survival rate. There are limited treatment options for these patients, and no targeted therapy or immunotherapy is available. Rational therapeutic targets remain to be found. In this review, we present the published literature and ...