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Wu, Xun Cheng, Yi-Shing Lisa Matthen, Mathew Yoon, Angela Schwartz, Gary K. Bala, Shashi Taylor, Alison M. Momen-Heravi, Fatemeh
Published in
Journal of Experimental & Clinical Cancer Research : CR
Background MicroRNAs (miRs) have been shown to play an important role in tumorigenesis, including in head and neck squamous cell carcinoma (HNSCC). The miR-34 family is thought to play a role in tumor suppression, but the exact mechanism of their action in HNSCC is not well understood. Moreover, the impact of chromosomal changes and mutation status...
Shi, Meng‐meng Zhu, Ying‐gang Yan, Jia‐yang Rouby, Jean‐jacques Summah, Hanssa Monsel, Antoine Qu, Jie‐ming
Rationale: The effects of mesenchymal stromal cells (MSCs) and MSC‐derived extracellular vesicles (MSC EVs) on multidrug‐resistant pseudomonas aeruginosa (MDR‐PA)‐induced pneumonia remain unclear.Materials and methods: MicroRNA array and RT‐PCR were used to select the major microRNA in MSC EVs. Human peripheral blood monocytes were obtained and iso...
Yang, Linqi Zhang, Wenqi Chopra, Saiyam Kaur, Deeepjyot Wang, Huibing Li, Meng Chen, Pingping Zhang, Wei
Published in
Current drug targets
Among the major components of green tea, epigallocatechin-3-gallate (EGCG) is the most effective for its anti-cancer characteristics. The bulk of studies provide the mechanisms of suppressive function of EGCG are involved in alteration of cancer cell cycle, development, and apoptosis through activation/inhibition of several signal pathways. Another...
Klein, Steven D Martinez-Agosto, Julian A
Published in
MicroRNA (Shariqah, United Arab Emirates)
We have previously described mosaic mutations in the RNase IIIb domain of DICER1that display global developmental delays, lung cysts, somatic overgrowth, macrocephaly and Wilms tumor. This constellation of phenotypes was classified as GLOW syndrome. Due to the phenotypic overlap between GLOW and syndromes caused by mutations in the PI3K/AKT/mTOR pa...
Daneshpour, Maryam Karimi, Behzad Omidfar, Kobra
Published in
Biosensors & bioelectronics
miRNAs are among the novel biomarkers that can be evaluated for sensitive and early cancer diagnosis. In the present study, an electrochemical nanobiosensor has been fabricated to detect two gastric cancer (GC) related miRNAs simultaneously. By employing Au nanoparticles- and [email protected] quantum dots-contained magnetic nanocomposites as electrochemica...
