Wang, Xiaoxue Qin, Wei Chen, Wenqian Liu, Huifang Zhang, Dan Zhang, Xianglin Li, Pengmei
Published in
Experimental and Therapeutic Medicine
Therapeutic drug monitoring is an essential tool when managing the therapeutic use of immunosuppressant cyclosporine A (CsA) in cases with solid organ transplantation. In China, the concentration of CsA is primarily measured using immunoassays. However, existing literature recommends mass spectrometry as the current gold standard for the quantitati...
Möller, Sören Debrabant, Birgit Halekoh, Ulrich Petersen, Andreas Kristian Gerke, Oke
Published in
Diagnostics
The Bland–Altman plot is the most common method to analyze and visualize agreement between raters or methods of quantitative outcomes in health research. While very useful for studies with two raters, a limitation of the classical Bland–Altman plot is that it is specifically used for studies with two raters. We propose an extension of the Bland–Alt...
Lelu, Alain Cadot, Martine
Fair evaluation of text clustering methods needs to clarify the relations between 1)pre-processing, resulting in raw term occurrence vectors, 2)data transformation, and 3)method in the strict sense. We have tried to empirically compare a dozen well-known methods and variants in a protocol crossing three contrasted open-access corpora in a few tens ...
Kuster, Roman P Grooten, Wilhelmus J A Blom, Victoria Baumgartner, Daniel Hagströmer, Maria Ekblom, Örjan
Published in
International journal of environmental research and public health
Sedentary Behavior (SB), defined as sitting with minimal physical activity, is an emergent public health topic. However, the measurement of SB considers either posture (e.g., activPal) or physical activity (e.g., ActiGraph), and thus neglects either active sitting or inactive standing. The aim of this study was to determine the true amount of activ...
Yuan, Shunzong Zheng, Naxin Zheng, Wenwen Jiang, Qian Qiao, Bing Jing, Huarong Li, Ying Qi, Xiaoyu Cao, Wenjing Song, Shiping
...
Published in
Clinical Chemistry and Laboratory Medicine (CCLM)
Ismail, Afefah Christensen, Julie Wulf Krakauer, Martin Søndergaard, Susanne Bonnichsen Zerahn, Bo Nygaard, Birte Bennedbæk, Finn Noe Kristensen, Bent Jensen, Lars Thorbjørn
Published in
Diagnostics
Background: In patients with primary hyperparathyroidism (PHPT) locating hyperfunctioning glands (HPGs) is crucial when planning minimally invasive surgery. Dual-isotope subtraction scintigraphy with 99mTc-MIBI/123Iodide using SPECT/CT and planar pinhole imaging (Method A) has previously shown a sensitivity >93%. However, the method is costly and t...
Gerke, Oke
Published in
International Journal of Environmental Research and Public Health
Bland–Altman limits of agreement and the underlying plot are a well-established means in method comparison studies on quantitative outcomes. Normally distributed paired differences, a constant bias, and variance homogeneity across the measurement range are implicit assumptions to this end. Whenever these assumptions are not fully met and cannot be ...
Mohanty, Rosaleena Mårtensson, Gustav Poulakis, Konstantinos Muehlboeck, J-Sebastian Rodriguez-Vieitez, Elena Chiotis, Konstantinos Grothe, Michel J Nordberg, Agneta Ferreira, Daniel Westman, Eric
...
Published in
Brain Communications
Graphical Abstract
Vílchez Rodríguez, Alberto González Cantó, Julia Esteve Poblador, Sara Valldecabres Ortiz, Carmen Estela Burriel, Pedro L.
Published in
Advances in Laboratory Medicine / Avances en Medicina de Laboratorio
Objectives Clinical laboratories should use only validated procedures. Precision is an important factor in the validation and verification of a new measurement procedure. Our objective was to verify the precision and trueness of different analysers used for the biochemical and immunochemical characterization of analytes. Methods Advia 1800®, Immuli...
von Meyer, Alexander Albert, Gesa Kunzelmann, Stefan Rank, Christopher Zerback, Rainer Imdahl, Roland
Published in
Clinical Chemistry and Laboratory Medicine (CCLM)
ObjectivesBiotin >20 ng/mL may interfere with the Elecsys® Troponin T-high sensitive assay (cTnT-hs; Roche Diagnostics International Ltd). We evaluated the performance of an updated assay, cTnT-hs*, which was designed to reduce biotin interference.MethodscTnT-hs* assay performance was assessed using up to two applications (18 min/9 min) on three an...
