Published in International Journal of Molecular Sciences
A global increase in the prevalence of metabolic syndromes and digestive tract disorders, like food allergy or inflammatory bowel disease (IBD), has become a severe problem in the modern world. Recent decades have brought a growing body of evidence that links the gut microbiome’s complexity with host physiology. Hence, understanding the mechanistic...
Published in Plants
Sorghum ( Sorghum bicolor (L.)) Moench is an important food for humans and feed for livestock. Sorghum contains dhurrin which can be degraded into toxic hydrogen cyanide. Here, we report the expression patterns of 14 candidate genes related to dhurrin ((S)-4-Hydroxymandelnitrile- β -D-glucopyranoside) metabolism and the effects of the gene expressi...
Published in Insects
Simple Summary The transcriptomic and metabolomic differences in rice leaves after infestation by the rice leaf folder Cnaphalocrocis medinalis were investigated for better understanding of the mechanisms of rice defenses against this species. The results suggest that C. medinalis infestation can induce rapid and precise defense responses involved ...
Published in International Journal of Molecular Sciences
Twelve articles (ten research papers and two reviews) included in the Special Issue entitled “Wheat and Barley: Acclimatization to Abiotic and Biotic Stress” are summed up here to present the latest research on the molecular background of adaptation to environmental stresses in two cereal species. Crucial research results were presented and discuss...
Published in Frontiers in Plant Science
Potassium (K) is essential for regulating plant growth and mediating abiotic stress responses. Elucidating the biological mechanism underlying plant responses to K-deficiency is crucial for breeding new cultivars with improved K uptake and K utilization efficiency. In this study, we evaluated the extent of the genetic variation among 543 wheat acce...
Published in Gut Microbes
Administration of probiotics has been linked to immune regulation and changes in gut microbiota composition, with effects on atopic dermatitis (AD). In this study, we investigated amelioration of the symptoms of AD using Lactobacillus paracasei KBL382 isolated from the feces of healthy Koreans. Mice with Dermatophagoides farinae extract (DFE)-induc...
Published in Microorganisms
Dietary factors modulate interactions between the microbiome, metabolome, and immune system. Sulforaphane (SFN) exerts effects on aging, cancer prevention and reducing insulin resistance. This study investigated effects of SFN on the gut microbiome and metabolome in old mouse model compared with young mice. Young (6–8 weeks) and old (21–22 months) ...
Published in Plant Biotechnology
Metabolome analysis of flavored vegetables, green spring onion ( Allium fistulosum ), Chinese chive ( A. tuberosum ), and their interspecies hybrid Negi-Nira chive, was conducted using liquid chromatography-Fourier transform ion cyclotron resonance-mass spectrometry, with ca. 2 ppm mass accuracy. Ion peaks in the chromatograms of four biological re...
Published in Plant Biotechnology
The model land plant Physcomitrella patens synthesizes flavonoids which may act as protectant of ultraviolet-B radiation. We aimed to uncover its flavonoid profile, for which metabolome analysis using liquid chromatography coupled with Ion trap/Orbitrap mass spectrometry was performed. From the 80% methanol extracts, 661 valid peaks were detected. ...
Published in Cancers
Simple Summary Hepatocellular carcinoma (HCC) is one of the diseases associated with human microbiome. The human microbiome is known to affect human disease through the metabolites. The aim of this study was to identify the pathways associated with HCC by integrating microbiome and metabolomic data via a novel pathway-based integrative method named...
