Jaschke, Nikolai P Funk, Alexander M Jonas, Sophie Riffel, Romy M Sinha, Anupam Wang, Andrew Pählig, Sophie Hofmann, Maura Altmann, Heidi Von Bonin, Simone
...
Published in
The Journal of clinical endocrinology and metabolism
Coronavirus disease 19 (COVID-19) trajectories show high interindividual variability, ranging from asymptomatic manifestations to fatal outcomes, the latter of which may be fueled by immunometabolic maladaptation of the host. Reliable identification of patients who are at risk of severe disease remains challenging. We hypothesized that serum concen...
Ratnaparkhi, Anuradha Sudhakaran, Jyothish
Published in
Frontiers in Physiology
Nutrient sensing and metabolic homeostasis play an important role in the proper growth and development of an organism, and also in the energy intensive process of reproduction. Signals in response to nutritional and metabolic status is received and integrated by the brain to ensure homeostasis. In Drosophila, the fat body is one of the key organs i...
Pan, Ming Ge, Ceng-Ceng Fan, Yi-Min Jin, Qi-Wang Shen, Bang Huang, Si-Yang
Published in
Frontiers in Microbiology
Toxoplasma gondii is an obligate intracellular zoonotic pathogen capable of infecting almost all cells of warm-blooded vertebrates. In intermediate hosts, this parasite reproduces asexually in two forms, the tachyzoite form during acute infection that proliferates rapidly and the bradyzoite form during chronic infection that grows slowly. Depending...
Santos, Alef Aragão Carneiro dos Rodrigues, Luiz Eduardo Alecrim-Zeza, Amanda Lins de Araújo Ferreira, Liliane Trettel, Caio dos Santos Gimenes, Gabriela Mandú Silva, Adelson Fernandes da Sousa-Filho, Celso Pereira Batista Serdan, Tamires Duarte Afonso Levada-Pires, Adriana Cristina
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Published in
Frontiers in Microbiology
Coronavirus disease 2019 (COVID-19) is triggered by the SARS-CoV-2, which is able to infect and cause dysfunction not only in lungs, but also in multiple organs, including central nervous system, skeletal muscle, kidneys, heart, liver, and intestine. Several metabolic disturbances are associated with cell damage or tissue injury, but the mechanisms...
Veloso, Tatiane Moraes de Souza da Fonseca, Adenilson Costa dos Santos, Gilson Jr
Published in
Frontiers in Photonics
Currently, light-emitting diodes (LEDs) are considered a substitute for low-power lasers in phototherapy protocols. LEDs enable photobiomodulation on biological tissues and are considered safe and economical. However, the molecular and metabolic mechanisms involved in LED-induced photobiomodulation are not yet fully understood. This review summariz...
Dominguez, Monica Truemper, Verena Mota, Ana Carolina Brüne, Bernhard Namgaladze, Dmitry
Published in
Frontiers in Immunology
ATP-citrate lyase (ACLY) is a key enzyme provoking metabolic and epigenetic gene regulation. Molecularly, these functions are exerted by the provision of acetyl-coenzyme A, which is then used as a substrate for de novo lipogenesis or as an acetyl-group donor in acetylation reactions. It has been demonstrated that ACLY activity can be positively reg...
Murakami, Shin Lacayo, Patricia
Published in
Frontiers in Aging Neuroscience
An increasing number of genes associated with Alzheimer’s disease (AD genes) have been reported. However, there is a lack of an overview of the genetic relationship between AD and age-related comorbidities, such as hypertension, myocardial infarction, and diabetes, among others. Previously, we used Reactome analysis in conjunction with the AD genes...
Placha, Iveta Gai, Francesco Pogány Simonová, Monika
Published in
Frontiers in Veterinary Science
Li, Wenpeng Li, Hui Yan, Chao Chen, Siyu Zhao, Xingbo
Published in
Frontiers in Genetics
Chicken is widely accepted by consumers because of its delicate taste and abundant animal protein. The rooster after castration (capon) is believed to show better flavor, however, the molecular changes of the underpinned metabolism after castration is not yet understood. In this study, we aimed to figure out the alternation of meat quality and unde...
Zhang, Xiaomeng Fang, Yaowei Yang, Guang Hou, Xiaoyue Hai, Yang Xia, Mengjie He, Fuxiang Zhao, Yaling Liu, Shu
Published in
Frontiers in Nutrition
Urolithin A (UA) has received considerable research attention because of its health benefits. However, only a few strains have been reported to produce UA from ellagic acid (EA), and the molecular mechanisms underlying the gut microbiota-mediated transformation of ellagic acid into urolithin A is limited. In the present study, a single strain FUA02...
