Ou, Jun Leong Sean Yang, Dimeng Liu, Mei Hui
Published in
Nutrients
Accumulating epidemiological evidence suggests that anthocyanin intake is associated with reduced risks of cardiometabolic disorders, highlighting the importance of incorporating the phytochemical in our diets. Numerous food-based intervention studies have examined, in controlled meal settings, the role of anthocyanin on cardiometabolic health; but...
O'Sullivan, Donnchadh Martin Linnane, Barry Hughes, Joanne Murphy, Anne-Marie
Published in
Archives of disease in childhood. Education and practice edition
Jackson, Thomas W Ryherd, Garret L Scheibly, Chris M Sasser, Aubrey L Guillette, T C Belcher, Scott M
Published in
Toxicological sciences : an official journal of the Society of Toxicology
There is compelling evidence that developmental exposure to toxic metals increases risk for obesity and obesity-related morbidity including cardiovascular disease and type 2 diabetes. To explore the hypothesis that developmental Cd exposure increases risk of obesity later in life, male, and female CD-1 mice were maternally exposed to 500 ppb CdCl2 ...
Sutherland, Duncan E K
Published in
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
COVID-19 has infected millions of people, with an estimated total dead in the hundreds of thousands. This has significantly impacted health care, including who is delivering it, how it is delivered, and how it is taught. This article describes challenges of the COVID-19 pandemic from the perspective of a Canadian nuclear medicine resident, includin...
Browne, Michael G Smock, Cameron S Roemmich, Ryan T
Published in
The Journal of physiology
We hypothesized that minimization of metabolic power could drive people to walk asymmetrically when one leg is constrained We studied healthy young adults and independently constrained one or both step lengths to be markedly shorter or longer than preferred using visual feedback When one leg was constrained to take a shorter or longer step than pre...
Pennisi, Alessandra Rötig, Agnès Roux, Charles-Joris Lévy, Raphaël Henneke, Marco Gärtner, Jutta Teke Kisa, Pelin Sarioglu, Fatma Ceren Yiş, Uluç Konczal, Laura L
...
Published in
Journal of medical genetics
Biallelic variants in PNPT1 cause a mitochondrial disease of variable severity. PNPT1 (polynucleotide phosphorylase) is a mitochondrial protein involved in RNA processing where it has a dual role in the import of small RNAs into mitochondria and in preventing the formation and release of mitochondrial double-stranded RNA into the cytoplasm. This, i...
Giugliani, Roberto Muschol, Nicole Keenan, Hillary A Dant, Mark Muenzer, Joseph
Published in
Archives of disease in childhood
Early diagnosis and treatment initiation are important factors for successful treatment of mucopolysaccharidosis type I (MPS I). The purpose of this observational study was to assess whether age at diagnosis and time to first treatment for individuals with MPS I have improved over the last 15 years. Data from the MPS I Registry (NCT00144794) for in...
Dawood, Nardeen B Yan, Kimberly L Shieh, Albert Livhits, Masha J Yeh, Michael W Leung, Angela M
Published in
Clinical endocrinology
Normocalcaemic primary hyperparathyroidism is a condition that can present with intermittent hypercalcemia or may evolve into hypercalcemic primary hyperparathyroidism. This milder biochemical entity remains incompletely understood because of a lack of long-term health outcomes regarding both medical and surgical approaches to its management. Medic...
Cetin, Zeynep Berker, Dilek Okudan, Berna Kilinckaya, Muhammed Turhan, Turan Catak, Merve
Published in
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Objective: Although animal studies claim that osteoprotegerin (OPG) is preventive on this system, there are conflicting results in human studies. The aim of this study was to investigate the role of OPG in the diagnosis and determination of cardivovascular risk in patients with polycystic ovary syndrome (PCOS), which is a multisystem effective dise...
McKiernan, Patrick J Squires, James E Squires, Robert H Vockley, Jerry Mazariegos, George V Soltys, Kyle Ganoza, Armando Strauss, Kevin Khanna, Ajai Sindhi, Rakesh
...
Published in
Clinical transplantation
Liver transplantation is a successful option for inherited metabolic disease yet little is published on the outcome among siblings. We report outcomes of siblings who have undergone liver transplantation for metabolic disease in a single program. Seventy-one siblings (35 males) from 33 individual families underwent liver transplantation since 1982....
