Development of setups for real-time analysis of the effluent of a microreactor by mass spectrometry
Compact and modular system architecture for a nano-resonator-mass spectrometer
Published in Frontiers in Chemistry
Mass measurements in the mega-to giga-Dalton range are essential for the characterization of natural and synthetic nanoparticles, but very challenging to perform using conventional mass spectrometers. Nano-electro-mechanical system (NEMS) based MS has demonstrated unique capabilities for the analysis of ultra-high mass analytes. Yet, system designs...
Recent advances in mass spectrometry-based proteomics and metabolomics in chronic rhinosinusitis with nasal polyps
Published in Frontiers in Immunology
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex and heterogeneous disease, typically diagnosed through endoscopy and computed tomography and treated with glucocorticoid or surgery. There is an urgent need to develop molecular-level diagnostic or prognostic tools to better understand the pathophysiology of CRSwNP. Proteomics and metab...
Study of electronic effects in organometallic complexes using mass spectrometry and their application in medicinal chemi...
Organometallic complexes are widely used in homogenous catalysis. The reactivity of a complex is linked to the ligands with which it is bound. Ligands can influence the reactivity of the metal center through their electronic and steric effects. It is therefore essential to know of these effects to choose the most suitable ligand when synthesizing o...
Correspondence comprehensive characterization of a brainstem aggregoma (light and heavy chain deposition disease).
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Published in Brain pathology (Zurich, Switzerland)
Dysregulation of intestinal epithelial electrolyte transport in canine chronic inflammatory enteropathy and the role of ...
Published in Frontiers in Veterinary Science
Chronic diarrhea is a hallmark sign of canine chronic inflammatory enteropathy (CIE), leading to fluid and electrolyte losses. Electrolyte homeostasis is regulated by the renin-angiotensin-aldosterone-system (RAAS), which might be involved in (counter-)regulating electrolyte losses in canine CIE. Whether and which electrolyte transporters are affec...
Comparative metabolomic profiling of Cupriavidus necator B-4383 revealed production of cupriachelin siderophores, one wi...
Published in Frontiers in Chemistry
Cupriavidus necator H16 is known to be a rich source of linear lipopeptide siderophores when grown under iron-depleted conditions; prior literature termed these compounds cupriachelins. These small molecules bear β-hydroxyaspartate moieties that contribute to a photoreduction of iron when bound as ferric cupriachelin. Here, we present structural as...
Potential of Fatty Acids in Treating Sarcopenia: A Systematic Review.
Published in Nutrients
This paper presents a systematic review of studies investigating the effects of fatty acid supplementation in potentially preventing and treating sarcopenia. PubMed, Embase, and Web of Science databases were searched using the keywords 'fatty acid' and 'sarcopenia'. Results: A total of 14 clinical and 11 pre-clinical (including cell and animal stud...
Emerging structural proteomics methodologies
Published in Frontiers in Analytical Science
Seasonal Variation in Plant Polyphenols and Related Bioactivities across Three Years in Ten Tree Species as Visualized b...
Published in Molecules (Basel, Switzerland)
The currently changing climates and environments place plants under many types of stresses that affect both their survival and levels of chemical defenses. The gradual induction of defenses in stressed plant populations could be monitored on a yearly basis unless a seasonal and yearly variation in natural defense levels obscures such monitoring sch...
