Wang, Zhen Mao, Yousheng Gao, Shugeng Li, Yin Tan, Lijie Daiko, Hiroyuki Liu, Shuoyan Chen, Chun Koyanagi, Kazuo He, Jie
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Published in
Annals of the New York Academy of Sciences
Until now, neoadjuvant therapy plus surgical resection of the primary tumor and potential metastatic lymph nodes (LNs) has been the current optimal treatment for locally advanced thoracic esophageal cancer (EC). LN metastasis is one of the most negative prognostic factors for thoracic esophageal squamous cell carcinoma (ESCC). However, the extent o...
Zou, Quan Ma, Sumei Zhou, Xinghu
ABSTRACT Objective: The objective of the study was to develop an association between clinicopathologic and sonographic features of patients with papillary thyroid microcarcinoma and the prevalence of lymph node metastasis. Subjects and methods: Clinicopathologic and sonographic features of 415 patients of papillary thyroid microcarcinoma with (n = ...
Zhou, Shaofei Miao, Lei Li, Tiantian Liu, Pu Zhou, Houmin
Published in
Cancer biotherapy & radiopharmaceuticals
Background: Colorectal cancer (CRC) has seriously endangered human health; despite significant advances in clinical treatment of CRC in recent years, clinically effective treatment options for CRC patients remain rare. Therefore, reducing the incidence and mortality of CRC is still a worldwide concern. This study aims to explore the clinical signif...
Koiwai, Akinobu Kogure, Takayuki Satoh, Mari Hirota, Morihisa Fukushi, Daisuke Sato, Tomonori Endo, Katsuya Takasu, Atsuko Meguro, Takayoshi Murakami, Kazuhiro
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Published in
Internal medicine (Tokyo, Japan)
A 51-year-old woman who presented with a large cystic liver tumor with mural nodules in the lateral segment developed Trousseau's syndrome. A mural nodule directly invaded her liver parenchyma. Metastatic nodules were detected in the right lobe and portal/paraaortic lymph nodes. The pathological findings showed mucin-producing adenocarcinoma cells ...
Cai, Wu Fan, Guohua Zhou, Hui Chen, Lei Ge, Jianxian Huang, Baoxing Zhou, Dandan Zeng, Jianfeng Miao, Qingqing Hu, Chunhong
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Published in
ACS applied materials & interfaces
Multimodal imaging-guided therapy holds great potential for precise theranostics of cancer metastasis. However, imaging agents enabling the convergence of complementary modalities with therapeutic functions to achieve perfect theranostics have been less exploited. This study reports the construction of a multifunctional nanoagent (FIP-99mTc) that c...
Shukla, Navika Osazuwa-Peters, Nosayaba Megwalu, Uchechukwu C
Published in
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
To determine the relationship between age and rate of lymph node metastasis, nodal burden of disease, as well as rate of lateral neck disease in papillary thyroid cancer, especially in patients aged 30 years. All analyses were adjusted for sex, race, and T classification. The overall rate of lymph node metastasis was 26.11%, which increased with de...
Liu, Jinhao Wang, Jikun Ma, Xueqian Feng, Yang Chen, Yanlei Wang, Yanping Xue, Dong Qiao, Shifeng
Published in
OncoTargets and therapy
Purpose Lymph node metastasis is one of the important prognostic factors of colorectal cancer, and an important index of individualized treatment. The purpose of this study is to use metabonomics to identify potential molecular markers of lymph node metastasis in colorectal cancer (CRC). Patients and Methods Peripheral blood samples of 223 CRC pati...
Jin, Yong Won Jia, Shuo Ashraf, Ahmed Bilal Hu, Pingzhao
Published in
Cancers
Simple Summary In recent years many successful models have been developed to perform various tasks in digital histopathology, yet, there is still a reluctance to fully embrace the new technologies in clinical settings. One of the reasons for this is that although these models have achieved high performance at the patch-level, their performance at t...
Zou, Quan Ma, Sumei Zhou, Xinghu
Published in
Archives of endocrinology and metabolism
The objective of the study was to develop an association between clinicopathologic and sonographic features of patients with papillary thyroid microcarcinoma and the prevalence of lymph node metastasis. Clinicopathologic and sonographic features of 415 patients of papillary thyroid microcarcinoma with (n = 102) or without (n = 313) lymph node metas...
Mori, Koichiro Toiyama, Yuji Okugawa, Yoshinaga Ichikawa, Takashi Nagano, Yuka Oki, Satoshi Shimura, Tadanobu Fujikawa, Hiroyuki Hiro, Junichiro Kobayash, Minako
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Published in
Oncology Letters
Accumulating evidence suggests that overexpression of heat shock protein 47 (HSP47) increases cancer progression, and that HSP47 level in the tumor-associated stroma may serve as a diagnostic marker in various cancers. The present study aimed to evaluate whether HSP47 gene expression in colorectal cancer (CRC) tissues could be used to identify lymp...