Chang, Runsheng Qi, Shouliang Yue, Yong Zhang, Xiaoye Song, Jiangdian Qian, Wei
Published in
Frontiers in Oncology
The heterogeneity and complexity of non-small cell lung cancer (NSCLC) tumors mean that NSCLC patients at the same stage can have different chemotherapy prognoses. Accurate predictive models could recognize NSCLC patients likely to respond to chemotherapy so that they can be given personalized and effective treatment. We propose to identify predict...
Dong, Xiaoxia Liu, Yongyu Deng, Xinzhou Shao, Jun Tian, Shuangyue Chen, Shuang Huang, Rongxin Lin, Ziao Chen, Chunli Shen, Li
...
Published in
Frontiers in Cell and Developmental Biology
Glycosyltransferases are frequently dysregulated in lung cancer. Core 1 β 1, 3-galactosyltransferase 1 (C1GALT1), an enzyme highly expressed in various cancers, is correlated with tumor initiation and development. However, the role of C1GALT1 in lung cancer remains poorly understood. In this study, through bioinformatic analysis and clinical valida...
Song, Xiaoping Xu, Xiangting Lu, Jiali Chi, Xiaoyuan Pang, Yue Li, Qingwei
Published in
Frontiers in Oncology
Lamprey immune protein (LIP), a novel protein derived from the Lampetra japonica, has been shown to exert efficient tumoricidal actions without concomitant damage to healthy cells. Our study aimed to ascertain the mechanisms by which LIP inhibits lung cancer cells, thus delineating potential innovative therapeutic strategies. LIP expression in lung...
Chen, Huan-Huan Zhang, Tie-Ning Wu, Qi-Jun Huang, Xin-Mei Zhao, Yu-Hong
Published in
Frontiers in Oncology
Globally, lung cancer is the most commonly diagnosed cancer and carries with it the greatest mortality rate, with 5-year survival rates varying from 4–17% depending on stage and geographical differences. For decades, researchers have studied disease mechanisms, occurrence rates and disease development, however, the mechanisms underlying disease pro...
Zhu, Zilan Zheng, Ziyi Liu, Jian
Published in
Frontiers in Oncology
COVID-19 and lung cancer are two severe pulmonary diseases that cause millions of deaths globally each year. Understanding the dysregulated signaling pathways between them can benefit treating the related patients. Recent studies suggest the critical role of reactive oxygen species (ROS) in both diseases, indicating an interplay between them. Here ...
Kagohashi, Katsunori Shiozawa, Toshihiro Miyazaki, Kunihiko Satoh, Hiroaki
Published in
The clinical respiratory journal
Shi, Hanxiao Niimi, Atsuko Takeuchi, Toshiyuki Shiogama, Kazuya Mizutani, Yasuyoshi Kajino, Taisuke Inada, Kenichi Hase, Tetsunari Hatta, Takahiro Shibata, Hirofumi
...
Published in
Cancer science
Ceramide synthase 6 (CERS6) promotes lung cancer metastasis by stimulating cancer cell migration. To examine the underlying mechanisms, we performed luciferase analysis of the CERS6 promoter region and identified the Y-box as a cis-acting element. As a parallel analysis of database records for 149 non-small-cell lung cancer (NSCLC) cancer patients,...
Ahmadi, Negar Mbuagbaw, Lawrence Finley, Christian Agzarian, John Hanna, Waël C Shargall, Yaron
Published in
The Journal of thoracic and cardiovascular surgery
Thoracic surgery is associated with significant rates of postoperative morbidity and postdischarge return to the hospital or emergency department (ED). This study aims to assess the impact of a novel integrated patient-centered, hospital-based multidisciplinary community program (Integrated Comprehensive Care [ICC]) on postdischarge outcomes in pat...
Rajaram, Ravi Rice, David C Li, Yanli Bruera, Eduardo Liu, Emelline Song, Chao Oh, Daniel S
Published in
The Journal of thoracic and cardiovascular surgery
To evaluate opioid administration after robotic lobectomy (RL) compared with video-assisted thoracic surgery (VATS) and open lobectomy in patients with lung cancer. Patients undergoing lobectomy for primary lung cancer between January 1, 2013, and September 30, 2015, were identified from the US Premier Hospital Perspective Database. The primary out...
Basnayake, Thilini L Valery, Patricia C Carson, Philip De Ieso, Paolo B
Published in
Internal medicine journal
Lung cancer is the most common cause of cancer-related mortality for both Indigenous and non-Indigenous Australians, and the death rate of lung cancer in Indigenous Australians is increasing. To provide a comprehensive description of patterns of lung cancer presentation, diagnosis, treatment and outcomes in Indigenous and non-Indigenous Australians...
