Giovannelli, Anna Chiara Köthe, Andreas Safai, Sairos Meer, David Zhang, Ye Weber, Damien Charles Lomax, Antony John Fattori, Giovanni
Published in
Physics in Medicine & Biology
Objective. Investigating the aspects of proton beam delivery to track organ motion with pencil beam scanning therapy. Considering current systems as a reference, specify requirements for next-generation units aiming at real-time image-guided treatments. Approach. Proton treatments for six non-small cell lung cancer (NSCLC) patients were simulated u...
Wei, Cui
Published in
Frontiers in Oncology
Background Though the matrix metalloproteinases (MMPs) are widely investigated in lung cancer (LC), however, almost no review systematically clarify their multi-faced roles in LC. Methods We investigated the expression of MMPs and their effects on survival of patients with LC, the resistance mechanisms of MMPs in anti-tumor therapy, the regulatory ...
Fang, Xiaolu Liu, Deyang Zhao, Jianzhong Li, Xiaojia He, Ting Liu, Baishan
Published in
Frontiers in Endocrinology
Background Senescence have emerged as potential factors of lung cancer risk based on findings from many studies. However, the underlying pathogenesis of lung cancer caused by senescence is not clear. In this study, we try to explain the potential pathogenesis between senescence and lung cancer through proteomics and metabonomics. And try to find ne...
Liu, Ying Ding, Wei Wang, Jianxun Ao, Xiang Xue, Junqiang
Published in
Frontiers in Oncology
Lung cancer (LC) is a heterogeneous disease with high malignant degree, rapid growth, and early metastasis. The clinical outcomes of LC patients are generally poor due to the insufficient elucidation of pathological mechanisms, low efficiency of detection and assessment methods, and lack of individualized therapeutic strategies. Non-coding RNAs (nc...
Zhang, Mengzhe Xiao, Zengtuan Xie, Yongjie Li, Zekun Zhang, Lianmin Zhang, Zhenfa
Published in
Frontiers in Pharmacology
Introduction: Lung adenocarcinoma is a common cause of mortality in patients with cancer. Recent studies have indicated that copper-related cell death may not occur in the same way as previously described. Long non-coding RNAs (lncRNAs) play a key role in the occurrence and development of tumors; however, the relationship between cuproptosis and ln...
Shahid, Ayaz Chen, Mengbing Yeung, Steven Parsa, Cyrus Orlando, Robert Huang, Ying
Published in
Frontiers in Pharmacology
Ganoderma lucidum (GL), commonly known as “Lingzhi”, is a well-known medicinal mushroom with antioxidant and anti-cancer activity. This study examined the effects of a commercial GL product (GLSF) containing the spore and fruiting body in a 30:8 ratio on tobacco smoke carcinogen-induced lung toxicity and carcinogenesis. The potential chemopreventiv...
Auriol, Camille Cantisano, Nicole Raynal, Patrick
Lung cancer is a disease with strong stigma due to stigmatization around smoking. Reducing stigma could be favorable for patients but requires to identify factors influencing this stigmatization. This study aimed to analyze people’s acceptability judgments regarding smokers’ behaviors concomitant to a lung cancer diagnosis. This study used a quanti...
Zhu, Youfeng Chen, Yang Xie, Di Xia, Dong Kuang, Huanming Guo, Xinmin Ning, Bo
Published in
Frontiers in Immunology
Background AKT3 appears to play a role in lung cancer. However, its role in ventilator-associated pneumonia is still unclear. Therefore, this study aimed to investigate the role of AKT3 in macrophages during ventilator-associated pneumonia. Methods The mRNA level of AKT3, Data from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), The ...
Seyedshahabedin, Mohammad M Howarth, Timothy P Mo, Lin Biancardi, Edwina Heraganahally, Subash S
Published in
Internal medicine journal
There is sparse evidence in the literature in relation to indications and outcomes among adult indigenous patients requiring a flexible bronchoscopy (FB). In this study, FB indications and outcomes between indigenous and non-indigenous patients were assessed. To assess the similarities and differences of FB indications and outcomes between indigeno...
Fu, Yufang Shi, Weiqing Zhao, Jing Cao, Xuyong Cao, Yuncen Lei, Mingxing Su, Xiuyun Cui, Qiu Liu, Yaosheng
Published in
Frontiers in Endocrinology
Background Health-related quality of life (HRQoL) is a critical aspect of overall well-being for patients with lung cancer, particularly those with metastatic spinal cord compression (MSCC). However, there is currently a lack of universal evaluation of HRQoL in this specific patient population. The aim of this study was to develop a nomogram that c...
