Boesen, Finn Nørgaard, Michael Skjerbæk, Anders Guldhammer Rasmussen, Peter Vestergaard Petersen, Thor Løvendahl, Brita Trénel, Philipp
Published in
Multiple sclerosis (Houndmills, Basingstoke, England)
Inpatient multidisciplinary rehabilitation (MDR) can improve health-related quality of life (HRQoL) in multiple sclerosis (MS) patients. However, the evidence of a long-term benefit is limited. To investigate the long-term effectiveness of inpatient MDR on HRQoL in MS patients. We conducted a randomized controlled partial crossover trial with 427 M...
Gelderblom, Hans Wagner, Andrew J Tap, William D Palmerini, Emanuela Wainberg, Zev A Desai, Jayesh Healey, John H van de Sande, Michiel A J Bernthal, Nicholas M Staals, Eric L
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Published in
Cancer
The objective of this study was to report on the long-term effects of pexidartinib on tenosynovial giant cell tumor (TGCT). This was a pooled analysis encompassing 3 pexidartinib-treated TGCT cohorts: 1) a phase 1 extension study (NCT01004861; 1000 mg/d; n = 39), 2) ENLIVEN patients randomized to pexidartinib (1000 mg/d for 2 weeks and then 800 mg/...
Kitazawa, Takeshi Shiba, Masato Nagaya, Hiroyuki Yuzuriha, Shunsuke
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Case Reports in Plastic Surgery & Hand Surgery
Here, we describe the case of an 80-year-old woman who presented with cranial dermoid cyst causing orbital disfigurement. The cyst was treated successfully with ethanol sclerotherapy and has shown no growth for 1 year.
Soer, Remko Reneman, Michiel F Mierau, Jochen O Schiphorst Preuper, Henrica R Stegeman, Patrick Speijer, Bert L G N Dijk, Hermien H Buwalda, Nynke Wolff, André P Coppes, Maarten H
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Published in
Spine
A before and after study cohort study. The aim of this study was to examine changes in health care costs after multidisciplinary spine care in patients with complex chronic back pain (CBP), to analyze the predictive value of patient and disease characteristics on health care costs, and to study the potential impact of biases concerning the use of r...
van Paassen, José G Britton, Andrea J Mitchell, Ruth J Street, Lorna E Johnson, David Coupar, Andrew Woodin, Sarah J
Published in
The New phytologist
Soil carbon (C) pools and plant community composition are regulated by nitrogen (N) and phosphorus (P) availability. Atmospheric N deposition impacts ecosystem C storage, but the direction of response varies between systems. Phosphorus limitation may constrain C storage response to N, hence P application to increase plant productivity and thus C se...
Wekker, V van Dammen, L Koning, A Heida, K Y Painter, R C Limpens, J Laven, J S E Roeters van Lennep, J E Roseboom, T J Hoek, A
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Published in
Human Reproduction Update
BACKGROUND Polycystic ovary syndrome (PCOS) is associated with cardiometabolic disease, but recent systematic reviews and meta-analyses of longitudinal studies that quantify these associations are lacking. OBJECTIVE AND RATIONALE Is PCOS a risk factor for cardiometabolic disease? SEARCH METHODS We searched from inception to September 2019 in MEDLIN...
Levy, Donald Caballero, Teresa Hussain, Iftikhar Reshef, Avner Anderson, John Baker, James Schwartz, Lawrence B. Cicardi, Marco Prusty, Subhransu Feuersenger, Henrike
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Pediatric Allergy, Immunology, and Pulmonology
Background: Hereditary angioedema (HAE) due to C1 inhibitor (C1INH) deficiency is characterized by recurrent attacks of edema of the skin and mucosal tissues. Symptoms usually present during childhood (mean age at first attack, 10 years). Earlier symptom onset may predict a more severe disease course. Subcutaneous (SC) C1INH is indicated for routin...
Hammad, Fayez T Al-Salam, Suhail Hammad, Waheed F Yasin, Javed Lubbad, Loay
Published in
American journal of physiology. Renal physiology
Following the release of short periods of unilateral ureteral obstruction (UUO), glomerular filtration rate (GFR) recovers by time. However, research in experimental animal models has demonstrated the presence of an ongoing element of renal interstitial fibrosis a few weeks following UUO reversal. Interstitial fibrosis can cause deterioration in GF...
Gong, Yan Liu, Wentai Wang, Runyu Brauer, Matthew Harris Zheng, Kristine Li, Wen
Published in
Micromachines
Reliable packaging for implantable neural prosthetic devices in body fluids is a long-standing challenge for devices’ chronic applications. This work studied the stability of Parylene C (PA), SiO2, and Si3N4 packages and coating strategies on tungsten wires using accelerated, reactive aging tests in three solutions: pH 7.4 phosphate-buffered saline...
Nilsson, Ida E K Åkervall, Sigvard Molin, Mattias Milsom, Ian Gyhagen, Maria
Published in
American journal of obstetrics and gynecology
The long-term effects of 1 or 2 consecutive obstetrical anal sphincter injuries on bowel continence are still inadequately investigated, and published results remain contradictory. This study aimed to present detailed descriptive measures of the current bowel incontinence 20 years after the first birth in women who had 2 vaginal deliveries with and...