Nutritional approaches in chronic liver diseases
Published in Frontiers in Nutrition
Nutritional approaches in chronic liver diseases
Socioeconomic Deprivation Weighs Heavily on Liver Fibrosis and Mortality After Hepatitis C Cure (ANRS CO22 Hepather).
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Although Hepatitis C virus (HCV) infection can be cured with direct-acting antivirals (DAA), some cured patients face a serious risk of advanced liver damage and early mortality. In order to avoid these two negative health outcomes, it is important to identify and assess related risk factors. Little is currently known about socioeconomic and behavi...
The mitochondrial translocator protein (TSPO, 18 kDa): A key multifunctional molecule in liver diseases.
Published in Biochimie
Translocator protein (TSPO, 18 kDa), previously known as peripheral-type benzodiazepine receptor, is an evolutionarily conserved and tryptophan-rich 169-amino-acid protein located on the outer mitochondrial membrane. TSPO plays a crucial role in various fundamental physiological functions and cellular processes. Its expression is altered in patholo...
Urinary Equol and Equol-Predicting Microbial Genera Are Favorably Associated with Body Fat Measures among Chinese Adults...
...Published in The Journal of nutrition
Many studies have investigated the intake of dietary isoflavones in relation to obesity risk, whereas the association using objective biomarkers of isoflavones, particularly equol (a gut-derived metabolite of daidzein with greater bioavailability than other isoflavones) has been less studied. In addition, the associations between equol and gut micr...
Potential treatment of glutathione in bullfrogs with abnormal hepatic lipid metabolism revealed by hepatic lipid metabol...
Published in Frontiers in Cellular and Infection Microbiology
Introduction With the continuous growth of bullfrog supply, it has become an important aquaculture species. Due to the lack of actionable industry standards and regulation, the misuse of anti-disease drugs and abnormal liver lipid metabolism in bullfrogs have become a major obstacle to the development of bullfrog aquaculture industry. Glutathione i...
A review of Phyllanthus urinaria L. in the treatment of liver disease: viral hepatitis, liver fibrosis/cirrhosis and hep...
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Published in Frontiers in Pharmacology
Due to the pathological production of liver disease in utility particularly complexity, the morbidity and mortality of liver disease including viral hepatitis, liver fibrosis/cirrhosis and hepatocellular carcinoma (HCC) are rapidly increasing worldwide. Considering its insidious onset, rapid progression and drug resistance, finding an effective the...
A novel morbillivirus and a novel betaherpesvirus infecting the Wood Mouse in the UK
Published in Acta Virologica
A novel morbillivirus and a novel betaherpesvirus are reported in the Wood Mouse (Apodemus sylvaticus) in the western United Kingdom (UK). The two viruses were found coinfecting an underweight host with abnormalities of the liver and were detected via deep sequencing of lung RNA and de novo assembly of substantial genome fragments. The phylogenetic...
Use of Intravenous Albumin: A Guideline From the International Collaboration for Transfusion Medicine Guidelines.
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Published in Chest
Albumin is used commonly across a wide range of clinical settings to improve hemodynamics, to facilitate fluid removal, and to manage complications of cirrhosis. The International Collaboration for Transfusion Medicine Guidelines developed guidelines for the use of albumin in patients requiring critical care, undergoing cardiovascular surgery, unde...
Patterns and unique features of infantile cholestasis among Arabs
Published in Frontiers in Pediatrics
Background Most of the literature on infantile cholestasis (IC) originated from Caucasian and Asian populations. The differential diagnosis of IC is very broad, and identification of etiology is challenging to clinicians because the list includes many entities with overlapping clinical, biochemical, and histological features. Thus, a structured, st...
Heme (dys)homeostasis and liver disease
Published in Frontiers in Physiology
Heme is essential for a variety of proteins involved in vital physiological functions in the body, such as oxygen transport, drug metabolism, biosynthesis of steroids, signal transduction, antioxidant defense and mitochondrial respiration. However, free heme is potentially cytotoxic due to the capacity of heme iron to promote the oxidation of cellu...
