Frishberg, Yaacov Hayes, Wesley Shasha-Lavsky, Hadas Sas, David J. Michael, Mini Sellier-Leclerc, Anne-Laure Hogan, Julien Willey, Richard Gansner, John M. Magen, Daniella
...
Published in
Frontiers in Pediatrics
Background Primary hyperoxaluria type 1 (PH1) is a genetic disorder resulting in overproduction of hepatic oxalate, potentially leading to recurrent kidney stones, nephrocalcinosis, chronic kidney disease, and kidney failure. Lumasiran, the first RNA interference therapeutic approved for infants and young children, is a liver-directed treatment tha...
Li, Peng Zhou, Hancong Yang, Yuzhu Wu, Mengjun Zhao, Di Wang, Lei Yi, Dan Hou, Yongqing
Published in
Frontiers in Nutrition
N-acetylcysteine (NAC) is a well-established antioxidant that offers exciting opportunities for intestinal health in weaned piglets, while the effects of NAC on muscle and liver has not been fully characterized. Therefore, the present study was performed to investigate the effects of dietary supplementation with NAC on muscle and liver in weaned pi...
Li, Chunli Bian, Li Fan, Guangtao Huang, Yilong Li, Jiang He, Bo
Published in
Frontiers in Medicine
Background Primary hepatic neuroendocrine tumors (PHNETs) are an utterly rare entity. The diagnosis of PHNETs could legitimize when an extrahepatic primary NET must always be excluded. PHNETs can achieve a high survival rate after complete surgical resection, however, most patients still have an 18% risk of recurrence within 5 years after surgery. ...
Francica, Giampiero
Published in
Exploration of Drug Science
Aim: This study aimed to evaluate the utility of the combined use of contrast-enhanced ultrasound (CEUS) and intracavitary CEUS (IC-CEUS) with diluted SonoVue in the management of percutaneous treatment for pyogenic liver abscess (PLA). Methods: 36 patients (23 males, 13 females; mean age 64 ± 13.9 years) with 39 PLAs (mean size 7.6 ± 3.4 cm) were ...
Han, Hui
Dysregulated lipid and cholesterol metabolism is associated with various metabolic diseases and even cancers. The liver is a critical organ for lipid and cholesterol metabolism. Previous evidence suggests that gut microbiota is associated with lipid and cholesterol metabolism, but little is known about the specific effects of gut microbiota on hepa...
Ward, Kiera Mulder, Edwin Frings-Meuthen, Petra O’Gorman, Donal J. Cooper, Diane
Published in
Frontiers in Physiology
Background Alterations in the circulating concentrations and target-tissue action of organokines underpin the development of insulin resistance in microgravity and gravity deprivation. The purpose of this study was to examine changes in circulating adropin, irisin, retinol binding protein-4 (RBP4), and the metabolic response of healthy young males ...
Li, Fan Xu, Jun Xie, Min Fei, Dan Zhou, Yaomin Li, Xiong Guang, Yelan Gong, Lihui Hu, Lizhen Feng, Fan
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Published in
Frontiers in Physiology
Background Long-term heat stress (HS) severely restricts the growth performance of beef cattle and causes various health problems. The gut microbiota plays a crucial role in HS-associated inflammation and immune stress involving lymphocyte function. This study investigated the effects of dietary tea polysaccharide (TPS), a natural acidic glycoprote...
Zhang, Jiaqi Wang, Wenzhao Hou, Xingyun Wu, Jia Wang, Yifan Fan, Jianling Zhang, Zhiyu Yuan, Zhizhong Sun, Cuifen Lu, Bin
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Published in
Frontiers in Endocrinology
Objective Alzheimer’s Disease (AD) is increasingly recognized as being associated with metabolic disorders, including Metabolic Associated Steatotic Liver Disease (MASLD). This study aimed to assess the relative risk of AD in individuals with MASLD. Methods In this retrospective cohort study, we analyzed data from individuals aged over 65 who under...
Van Der Hoek, Jan L. Krommendijk, Marleen E. Manohar, Srirang Arens, Jutta Groot Jebbink, Erik
Published in
Transplant International
Wang, Wenjia Han, Yiheng Yin, Wen Wang, Qiaozhi Wu, Yi Du, Maobo
Published in
Frontiers in Microbiology
Ulcerative colitis (UC), characterized by disrupted intestinal barrier integrity and chronic inflammation, was modeled in mice via dextran sulfate sodium (DSS) induction. This study explored the therapeutic potential of berberine-evodiamine (BBR-EVO), bioactive components of the traditional Chinese medicine Yulian decoction, in DSS colitis. BBR-EVO...
