Montoro, Marta De Fine Licht, Henrik H Sigsgaard, Lene
Published in
Insect science
The predatory bug, Orius majusculus (Reuter), is an important predator of thrips commercially produced for augmentative releases using the eggs of the Mediterranean flour moth Ephestia kuehniella (Zeller). In this study, we assessed the potential for using frozen adults of fruit flies, Drosophila melanogaster (Meigen), either as nymphal rearing die...
Zhang, Zhiqin Ni, Lihua Zhang, Lian Zha, Dongqing Hu, Chun Zhang, Lingli Feng, Huiling Wei, Xiaobao Wu, Xiaoyan
Published in
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Background Abnormal lipid deposition in the progress of diabetic nephropathy (DN) plays an important role in a number of studies that have shown that SGLT2 inhibitor (SGLT2i) empagliflozin plays an important role in lipid metabolism, but its mechanism is still unclear. Methods We aimed to explore the effect of empagliflozin on lipid levels in kidne...
Rotimi, Oluwakemi A. Onuzulu, Chinonye D. Dewald, Alisa L. Ehlinger, Jessa Adelani, Isaacson B. Olasehinde, Olutola E. Rotimi, Solomon O. Goodrich, Jaclyn M.
Published in
International Journal of Environmental Research and Public Health
Aflatoxins are toxic compounds produced by molds of the Aspergillus species that contaminate food primarily in tropical countries. The most toxic aflatoxin, aflatoxin B1 (AFB1), is a major cause of hepatocellular carcinoma (HCC) in these countries. In sub-Saharan Africa, aflatoxin contamination is common, and perinatal AFB1 exposure has been linked...
Pathan-Chhatbar, Salma Drechsler, Carina Richter, Kirsten Morath, Anna Wu, Wei OuYang, Bo Xu, Chenqi Schamel, Wolfgang W
Published in
Frontiers in cell and developmental biology
Biological membranes consist of hundreds of different lipids that together with the embedded transmembrane (TM) proteins organize themselves into small nanodomains. In addition to this function of lipids, TM regions of proteins bind to lipids in a very specific manner, but the function of these TM region-lipid interactions is mostly unknown. In thi...
Carravilla, Pablo Nieva, José L Eggeling, Christian
Published in
Viruses
Human immunodeficiency virus (HIV) infection constitutes a major health and social issue worldwide. HIV infects cells by fusing its envelope with the target cell plasma membrane. This process is mediated by the viral Env glycoprotein and depends on the envelope lipid composition. Fluorescent microscopy has been employed to investigate the envelope ...
Chignon, Arnaud Bon-Baret, Valentin Boulanger, Marie-Chloé Bossé, Yohan Mathieu, Patrick
Published in
Arteriosclerosis, thrombosis, and vascular biology
Mineralization of cardiovascular structures including blood vessels and heart valves is a common feature. We postulate that ectopic mineralization is a response-to-injury in which signals delivered to cells trigger a chain of events to restore and repair tissues. Maladaptive response to external or internal signals promote the expression of danger-...
Iossa, Domenico Vitrone, Martina Gagliardi, Massimo Falco, Erasmo Ragone, Enrico Zampino, Rosa Durante-Mangoni, Emanuele
Published in
Annals of Translational Medicine
Background Hepatitis C virus (HCV) infection affects lipid metabolism. We investigated the impact of direct-acting antiviral (DAA) treatment on lipid metabolism in chronic hepatitis C (CHC), with a focus on the effects of anthropometric parameters and liver histology. We also analyzed the dynamics of metabolic indexes used to estimate cardiovascula...
Petkevicius, Kasparas Bidault, Guillaume Virtue, Sam Jenkins, Benjamin Dugourd, Aurelien Saez-Rodriguez, Julio Stienstra, Rinke Koulman, Albert Vidal-Puig, Antonio
Tissue-resident macrophages are required for homeostasis, but also contribute to tissue dysfunction in pathophysiological states. The sympathetic neurotransmitter norepinephrine (NE) induces an anti-inflammatory and tissue-reparative phenotype in macrophages. As NE has a well-established role in promoting triglyceride lipolysis in adipocytes, and m...
Salimi, Mohammadhossein Villiger, Martin Tabatabaei, Nima
Published in
Journal of Biomedical Optics
Significance: Photothermal optical coherence tomography (PT-OCT) has the promise to offer structural images coregistered with chemical composition information, which can offer a significant impact in early detection of diseases such as atherosclerosis. Aim: We take the first step in understanding the relation between PT-OCT signals and the endogeno...
Liu, Yihao Wang, Jie Zhou, Xiaomin Cao, Haigang Zhang, Xiaoyu Huang, Kuilong Li, Xiao Yang, Gongshe Shi, Xin'e
Published in
Molecular therapy. Nucleic acids
Skeletal muscle is an important metabolic organ of the body, and impaired skeletal muscle differentiation can result in a wide range of metabolic diseases. It has been shown that microRNAs (miRNAs) play an important role in skeletal muscle differentiation. The aim of this study was to investigate the role of mmu-miR-324-5p in the differentiation of...