Lin, Yifen Zhong, Xiangbin Xiong, Zhenyu Zhang, Shaozhao Liu, Menghui Fan, Yongqiang Huang, Yiquan Sun, Xiuting Zhou, Huimin Xu, Xingfeng
...
Published in
Frontiers in Physiology
AimTo determine whether long-term intensity of glycemic exposure (IGE) during young adulthood is associated with multiple target organs function at midlife independent of single fasting glucose (FG) measurement. MethodsWe included 2,859 participants, aged 18–30 years at Y0, in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. IGE...
Ahmed, Heba Mostafa Ameen, Emad El-Deen Awad, Mohammad Shafiq Botrous, Osama Ezzat
Published in
Vascular Health and Risk Management
Background Children with nephrotic syndrome (NS) are at a greater risk of atherosclerosis due to recurrent exposures to hyperlipidemia, hypertension, and immunosuppressive medications. CIMT (carotid intima media thickness) is a reliable marker for assessment of atherosclerosis of large and medium-sized blood vessels; endothelial dysfunction and inc...
Palupi-Baroto, Retno Hermawan, Kristia Murni, Indah Kartika Nurlitasari, Tiara Prihastuti, Yuli Sekali, Debora Roselita Karo Ambarsari, Cahyani Gita
Published in
International Journal of Nephrology and Renovascular Disease
Introduction Left ventricular hypertrophy (LVH) is the most common cardiac abnormality in chronic kidney disease (CKD). Changes in cardiac geometry and functions may occur in an early stage and worsen as CKD progresses. Recently, the role of fibroblast growth factor 23 (FGF23) is being highlighted and investigated in CKD-related cardiomyopathy. How...
Ueda, Yu Kovacs, Samantha Reader, Rachel Roberts, Jeffrey A. Stern, Joshua A.
Published in
Frontiers in Veterinary Science
In a colony of rhesus macaques at California National Primate Research Center (CNPRC), naturally occurring hypertrophic cardiomyopathy (HCM) classified by left ventricular hypertrophy without obvious underlying diseases has been identified during necropsy over the last two decades. A preliminary pedigree analysis suggested a strong genetic predispo...
Hou, Miao Cao, Lei Ding, Yueyue Chen, Ye Wang, Bo Shen, Jie Zhou, Wanping Huang, Jie Xu, Qiuqin Lv, Haitao
...
Published in
Frontiers in Pediatrics
Aim: Hypertension is associated with cardiac structural and functional changes, including left ventricular hypertrophy (LVH) and LV systolic dysfunction diastolic dysfunction. Neutrophil-to-lymphocyte ratio (NLR) is a novel inflammatory biomarker associated with cardiovascular diseases. The current study aimed to evaluate NLR in children with newly...
Radloff, Judith Pagitz, Maximilian Andrukhova, Olena Oberbauer, Rainer Burgener, Iwan A. Erben, Reinhold G.
Published in
Frontiers in Physiology
BackgroundChronic kidney disease (CKD) is accompanied by increases in circulating fibroblast growth factor 23 (FGF23) and aldosterone levels. Here, we tested the hypothesis that aldosterone may be one of the driving forces behind increased FGF23 secretion in CKD. MethodsUsing data from a prospective study in humans, a retrospective study in dogs an...
Wenzel, Kristin Krämer, Elisabeth Geertz, Birgit Carrier, Lucie Felix, Stephan B. Könemann, Stephanie Schlossarek, Saskia
Published in
Frontiers in Physiology
The ubiquitin-proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the main proteolytic systems involved in cellular homeostasis. Since cardiomyocytes, as terminally differentiated cells, lack the ability to share damaged proteins with their daughter cells, they are especially reliant on these protein degradation systems for their ...
Mahal, Shanan Tarun, Tushar Datta, Sorabh Aggarwal, Kul
Published in
Cureus
Apical hypertrophic cardiomyopathy (ApHCM) is a clinical challenge when presenting with symptoms of angina plus shortness of breath. An appropriate diagnosis of concurrent coronary artery disease (CAD) is needed for proper diagnosis, risk stratification, and management. We present a case of a 64-year-old gentleman with a history of ApHCM and CAD wi...
Ha, Edward T. Cohen, Marc Peterson, Stephen J. Aronow, Wilbert S.
Published in
Archives of Medical Sciences. Atherosclerotic Diseases
Introduction The effect of the type of left ventricular hypertrophy in patients presenting with an acute coronary syndrome (ACS) on long-term outcomes is ill-defined. The purpose of this study was to investigate the prognostic effect of concentric (CH) or eccentric hypertrophy (EH) on adverse outcomes in patients presenting with ACS undergoing perc...
Querfeld, Uwe
Published in
Acta paediatrica (Oslo, Norway : 1992)
Children suffering from chronic kidney disease (CKD) have the apparent highest risk for the development of cardiovascular disease (CVD) at a young age. While symptoms of CVD are characteristically absent in childhood and adolescence, remodelling of the myocardium, medium and large-sized arteries and of the microcirculation is clinically significant...
