Janssen, Anne Breusegem, Sophia Larrieu, Delphine
Any given cell type has an associated "normal" nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity. Deviations from this can be indicative of diseases such as cancer or premature aging syndrome. To accurately assess nuclear abnormalities, it is important to use quantitative measures of nucl...
f., anne
Any given cell type has an associated “normal” nuclear morphology, which is important to maintain proper cellular functioning and safeguard genomic integrity. Deviations from this can be indicative of diseases such as cancer or premature aging syndrome. To accurately assess nuclear abnormalities, it is important to use quantitative measures of nucl...
Padilla-Mejia, Norma E Makarov, Alexandr A Barlow, Lael D Butterfield, Erin R Field, Mark C
Published in
Nucleus (Austin, Tex.)
Eukaryotic cells arose ~1.5 billion years ago, with the endomembrane system a central feature, facilitating evolution of intracellular compartments. Endomembranes include the nuclear envelope (NE) dividing the cytoplasm and nucleoplasm. The NE possesses universal features: a double lipid bilayer membrane, nuclear pore complexes (NPCs), and continui...
Niethammer, Philipp
The cell nucleus is best known as the container of the genome. Its envelope provides a barrier for passive macromolecule diffusion, which enhances the control of gene expression. As its largest and stiffest organelle, the nucleus also defines the minimal space requirements of a cell. Internal or external pressures that deform a cell to its physical...
langer;, max
Although both the petiole and lamina of foliage leaves have been thoroughly studied, the transition zone between them has often been overlooked. We aimed to identify objectively measurable morphological and anatomical criteria for a generally valid definition of the petiole–lamina transition zone by comparing foliage leaves with various body plans ...
Cosgrove, Brian D Loebel, Claudia Driscoll, Tristan P Tsinman, Tonia K Dai, Eric N Heo, Su-Jin Dyment, Nathaniel A Burdick, Jason A Mauck, Robert L
Published in
Biomaterials
Exogenous mechanical cues are transmitted from the extracellular matrix to the nuclear envelope (NE), where mechanical stress on the NE mediates shuttling of transcription factors and other signaling cascades that dictate downstream cellular behavior and fate decisions. To systematically study how nuclear morphology can change across various physio...
Pruvost, Mathilde Moyon, Sarah
Published in
Life
Oligodendroglial cells are the myelinating cells of the central nervous system. While myelination is crucial to axonal activity and conduction, oligodendrocyte progenitor cells and oligodendrocytes have also been shown to be essential for neuronal support and metabolism. Thus, a tight regulation of oligodendroglial cell specification, proliferation...
Groves, Norman Reid Biel, Alecia Moser, Morgan Mendes, Tyler Amstutz, Katelyn Meier, Iris
Published in
Nucleus (Austin, Tex.)
The functional organization of the plant nuclear envelope is gaining increasing attention through new connections made between nuclear envelope-associated proteins and important plant biological processes. Animal nuclear envelope proteins play roles in nuclear morphology, nuclear anchoring and movement, chromatin tethering and mechanical signaling....
Tang, Ke Li, Jianxiao Huang, Tianji Zhong, Weiyang Luo, Xiaoji Quan, Zhengxue
Published in
International Journal of Medical Sciences
A retrospective study investigated and compared the results of lamina with spinous process (LSP), transverse process strut (TPS) and iliac graft (IG) as bone graft in thoracic single-segment spinal tuberculosis(TB) with the one-stage posterior approach of debridement, fusion and internal instrumentation. 99 patients treated from January 2012 to Dec...
Bernstein, S. L. Guo, Y. Kerr, C. Fawcett, R. J. Stern, J. H. Temple, S. Mehrabian, Z.
Published in
Proceedings of the National Academy of Sciences of the United States of America
Retinal ganglion cell axons forming the optic nerve (ON) emerge unmyelinated from the eye and become myelinated after passage through the optic nerve lamina region (ONLR), a transitional area containing a vascular plexus. The ONLR has a number of unusual characteristics: it inhibits intraocular myelination, enables postnatal ON myelination of growi...