john, kristen m. wenn, peter hai, ofek zeltser, roman makaryus, amgad n.
Background/Objectives: Coronary artery disease (CAD) is a common and treatable cause of heart failure (HF), but ischemic evaluation is often overlooked when evaluating patients with new-onset HF. Here, we sought to discern demographic and clinical predictors of ischemic workup in patients with newly diagnosed HF. Methods: A retrospective study of 2...
grant, william b. boucher, barbara j.
Background/Objectives: Prospective cohort studies are useful for studying how biomolecular status affects risk of adverse health outcomes. Less well known is that the longer the follow-up time, the lower the association (or “apparent effect”) due to “regression dilution”. Here, we evaluate how follow-up interval from baseline to “event” affects the...
Dohle, Esmee Lewis, Benjamin Agarwal, Smriti Warburton, Elizabeth A Evans, Nicholas R
BACKGROUND: Frailty-the loss of physiological reserve to withstand a stressor event-is associated with poorer outcomes following acute stroke reperfusion therapies. However, the mechanisms underlying this relationship are poorly understood. This study investigated the association between frailty and penumbral volumes in hyperacute ischemic stroke. ...
horváth, lászló verzár, zsófia csákvári, tímea szapáry, lászló domján, péter bálint, csaba khatatbeh, haitham ali, amira mohammed pakai, annamária
Cerebrovascular diseases are the leading cause of death and disability. The epidemiological background and predisposing factors have been the basis of many studies. We aimed to assess the effect of seasonal variability and meteorological factors on stroke incidence in Hungary. National and county-level secondary data were assessed for 2018–2019. We...
Zhang, Lingfeng Xie, Gang Zhang, Yue Li, Junlin Tang, Wuli Yang, Ling Li, Kang
Published in
Frontiers in Neuroscience
Purpose This research aimed to create a machine learning model for clinical-radiomics that utilizes unenhanced computed tomography images to assess the likelihood of malignant cerebral edema (MCE) in individuals suffering from acute ischemic stroke (AIS). Methods The research included 179 consecutive patients with AIS from two different hospitals. ...
zaharia, andrei-lucian oprea, violeta diana coadă, camelia alexandra tănase, claudiu elisei ionescu, ana-maria chirila, sergiu ioachim mihailov, raul tutunaru, dana lungu, mihaiela
Stroke is a leading cause of death and severe disability worldwide. Rapid diagnosis is critical to ensure the timely administration of medical treatment. Given that in some cases CT scans fail to show the classic clinical signs of stroke, we aimed to evaluate the diagnostic capacity of adiponectin levels and their association with the clinical para...
maida, carlo domenico norrito, rosario luca rizzica, salvatore mazzola, marco scarantino, elisa rita tuttolomondo, antonino
Stroke represents one of the neurological diseases most responsible for death and permanent disability in the world. Different factors, such as thrombus, emboli and atherosclerosis, take part in the intricate pathophysiology of stroke. Comprehending the molecular processes involved in this mechanism is crucial to developing new, specific and effici...
aljamal, danny iyengar, priya s. nguyen, tammy t.
Despite several promising preclinical studies performed over the past two decades, there remains a paucity of market-approved drugs to treat chronic lower extremity wounds in humans. This translational gap challenges our understanding of human chronic lower extremity wounds and the design of wound treatments. Current targeted drug treatments and de...
Makharia, Archita Agarwal, Ayush Garg, Divyani Vishnu, Venugopalan Y. Srivastava, M. V. Padma
Published in
Annals of Indian Academy of Neurology
Stroke is the second leading cause of death and a major cause of disability worldwide. Stroke severity scales serve as reliable means to track a patient's neurological deficit, predict outcome, and guide treatment decisions in clinical practice. The National Institute of Health Stroke Scale (NIHSS) was introduced over 30 years ago, marking a signif...
Yang, Yifan Gao, Li Shen, Fuwei Miao, Jiaodan Liu, Hua
Published in
Frontiers in Endocrinology
Objective To investigate the relationship between serum uric acid (SUA) levels and ischemic stroke in young patients in the Ganzi Tibetan plateau area. Methods A cross-sectional survey was undertaken from January 2020 to June 2023 involving young patients (age: 15–45 years) diagnosed with ischemic stroke. The survey was conducted at the Department ...
