Bayram, Pinar Karamese, Selina Aksak Erol, Huseyin Serkan Ozdemir, Bengul Toktay, Erdem Salum, Cagatay
Published in
Journal of histotechnology
In this study, the main hypothesis is that paeoniflorin may inhibit some cellular processes such as oxidative stress and inflammation. For this reason, we aimed to investigate the potential protective effects of a natural compound, paeoniflorin, on rat model of ovarian ischemia-reperfusion injury by detecting the oxidative stress parameters and inf...
Li, Shuai Zhang, Weixun Hu, Xiaopeng
Published in
Frontiers in Immunology
Background Oxidative stress is the primary cause of ischemia-reperfusion injury (IRI) in kidney transplantation, leading to delayed graft function (DGF) and implications on patient health. Necroptosis is believed to play a role in renal IRI. This research presents a comprehensive analysis of necroptosis-related genes and their functional implicatio...
Ludwig, Kristina Chichelnitskiy, Evgeny Kühne, Jenny F. Wiegmann, Bettina Iske, Jasper Ledwoch, Nadine Ius, Fabio Beushausen, Kerstin Keil, Jana Iordanidis, Susanne
...
Published in
Frontiers in Immunology
Introduction Following heart transplantation, a cascade of immunological responses is initiated influencing the clinical outcome and long-term survival of the transplanted patients. The anti-inflammatory cytokine interleukin-10 (IL-10) was shown to be elevated in the blood of heart transplant recipients directly after transplantation but the releas...
Lisnyy, I I Zakalska, K A Burlaka, A A Lysykh, S A Efimenko, O V
Published in
Experimental oncology
The intermittent Pringle maneuver remains the major technique for controlling hemorrhage during liver surgery. Nevertheless, this procedure involves a risk of triggering a cascade of pathological changes resulting in the ischemia-reperfusion injury (I/R) effect. The pharmacological prevention of this I/R injury represents a promising approach. The ...
Böning, Andreas Flicker, Luisa Rodriguez-Montesinos, Julian Cabrera-Fuentes, Hector Preissner, Klaus T Niemann, Bernd Taghiyev, Zulfugar T
Published in
Perfusion
We have previously shown that remote ischemic preconditioning (RIP), which utilizes in part the extracellular RNA (eRNA)/RNase1 pathway, can induce ischemic tolerance in humans. Because RIP has thus far been tested only with four cycles of extremity ischemia/reperfusion, we investigated the influence of six cycles of ischemia on the eRNA/RNase1 pat...
Chen, Zijian Liu, Yangqi Lin, Zeying Huang, Weizhe
Published in
Frontiers in Immunology
Transplantation is an important life-saving therapeutic choice for patients with organ or tissue failure once all other treatment options are exhausted. However, most allografts become damaged over an extended period, and post-transplantation survival is limited. Ischemia reperfusion injury (IRI) tends to be associated with a poor prognosis; result...
Guo, Zhenya Fan, Xiude Nagy, Laura E. Tomlinson, Stephen Yuan, Guandou
Published in
Frontiers in Immunology
Kumphune, Sarawut Piot, Christophe Barrere-Lemaire, Stéphanie
Published in
Frontiers in Cardiovascular Medicine
Thong-Asa, Wachiryah Puenpha, Kanthaporn Lairaksa, Thannaporn Saengjinda, Siriwipha
Published in
Experimental animals
Cerebral ischemia reperfusion (IR) injury as found in stroke is a complex and heterogeneous disorder and closely related to disability and death. Today, nutraceuticals and protective therapy to increase neuronal integrity and prevent pathological complication are common. We investigated the neuroprotective effect of betanin against cerebral IR inju...
Delgado-Betancourt, Viviana Chinda, Kroekkiat Mesirca, Pietro Barrère, Christian Covinhes, Aurélie Gallot, Laura Vincent, Anne Bidaud, Isabelle Kumphune, Sarawut Nargeot, Joël
...
Published in
Frontiers in Cardiovascular Medicine
Background Acute myocardial infarction (AMI) is the major cause of cardiovascular mortality worldwide. Most ischemic episodes are triggered by an increase in heart rate, which induces an imbalance between myocardial oxygen delivery and consumption. Developing drugs that selectively reduce heart rate by inhibiting ion channels involved in heart rate...
