Chow, Rosalind S.
Published in
Frontiers in Veterinary Science
Fluid therapy is administered to veterinary patients in order to improve hemodynamics, replace deficits, and maintain hydration. The gradual expansion of medical knowledge and research in this field has led to a proliferation of terms related to fluid products, fluid delivery and body fluid distribution. Consistency in the use of terminology enable...
Richards, Toby Breymann, Christian Brookes, Matthew J. Lindgren, Stefan Macdougall, Iain C. McMahon, Lawrence P. Munro, Malcolm G. Nemeth, Elizabeta Rosano, Giuseppe M. C. Schiefke, Ingolf
...
Published in
Annals of Medicine
Iron deficiency is a common cause of morbidity and can arise as a consequence or complication from many diseases. The use of intravenous iron has increased significantly in the last decade, but concerns remain about indications and administration. Modern intravenous iron preparations can facilitate rapid iron repletion in one or two doses, both for...
Pollock, Richard F Muduma, Gorden
Published in
ClinicoEconomics and Outcomes Research: CEOR
Background and Aims Iron deficiency anemia (IDA) is a common sequela of inflammatory bowel disease (IBD), arising from the combined effects of gastrointestinal blood loss and reduced iron absorption. Given this, intravenous (IV) iron should be considered as the first-line treatment in patients with clinically active IBD. The present study evaluated...
Dong, Wenliang Chen, Min Wang, Jiaxue Xia, Lin Wang, Qian Nie, Xiaoyan Feng, Yufei Fang, Yi
Published in
Immunotherapy
Aim: This meta-analysis aimed to evaluate the pharmacokinetics, efficacy, safety and immunogenicity of rHuPH20-facilitated subcutaneous (SC) administration of monoclonal antibody compared with intravenous (IV) administration for patients with cancer. Materials & methods: Outcomes included trough concentrations (Ctrough), overall response rate, adve...
Zhang, Wei Liu, Yi Yu, Jing Li, Dongze Jia, Yu Zhang, Qin Gao, Yongli Liao, Xiaoyang
Published in
Medicine
Introduction: Cardiac arrest refers to the sudden termination of cardiac ejection function due to various causes. Adrenaline is an important component of resuscitation among individuals experiencing cardiac arrest. The adrenaline delivery method chiefly involved intraosseous infusion and intravenous access. However, the impact of different adrenali...
Lorscheider, Mathilde Gaudin, Alice Nakhlé, Jessica Veiman, Kadi-Liis Richard, Joël Chassaing, Christophe
Published in
Therapeutic delivery
Global cancer prevalence has continuously increased in the last decades despite substantial progress achieved for patient care. Cancer is no longer recognized as a singular disease but as a plurality of different ones, leading to the important choice of the drug administration route and promoting the development of novel drug-delivery systems (DDS)...
Mylavarapu, Goutham Fleck, Robert J. Ok, Michale S. Ding, Lili Kandil, Ali Amin, Raouf S. Das, Bobby Mahmoud, Mohamed
Published in
Journal of Clinical Medicine
General anesthesia decreases the tone of upper airway muscles in a dose-dependent fashion, potentially narrowing the pharyngeal airway. We examined the effects of adding ketamine on the airway configuration after dexmedetomidine administration in spontaneously breathing children with normal airways. 25 children presenting for Magnetic Resonance Ima...
Vawda, Reaz Badner, Anna Hong, James Mikhail, Mirriam Dragas, Rachel Xhima, Kristiana Jose, Alejandro Fehlings, Michael G.
Published in
Stem Cells and Development
Cell therapy offers significant promise for traumatic spinal cord injury (SCI), which despite many medical advances, has limited treatment strategies. Able to address the multifactorial and dynamic pathophysiology of SCI, cells present various advantages over standard pharmacological approaches. However, the use of live cells is also severely hampe...
Zhu, He Chen, Yaobing Huang, Shaoqiang Sun, Xingfeng
Published in
Drug Design, Development and Therapy
Purpose The combination of dezocine and sufentanil is often used for postoperative analgesia in China and other areas, but the interaction of both two drugs is still unclear. The purpose of this study was to evaluate the interaction of the analgesic effects of dezocine and sufentanil in the patients after gynecological laparoscopic surgery. Patient...
Morse, James D. Cortinez, L. Ignacio Anderson, Brian J.
Published in
Journal of Clinical Medicine
A universal pharmacokinetic model was developed from pooled paediatric and adult data (40.6 postmenstrual weeks, 70.8 years, 3.1–152 kg). A three-compartment pharmacokinetic model with first-order elimination was superior to a two-compartment model to describe these pooled dexmedetomidine data. Population parameter estimates (population parameter v...