Halhalli, Huseyin C Uslu, Tolga
Published in
Cureus
Introduction: Pediatric intoxication cases are one of the important emergency room admissions. Early diagnosis and treatment are important in reducing morbidity and mortality. The prevalence and exposure types of pediatric intoxications have social and regional differences. In this study, we aimed to retrospectively analyze the demographic and epid...
Harvey, Alistair J. Seedhouse, Molly
Published in
Perception
We used an enumeration task to address the question of whether acute alcohol intoxication reduces cognitive or perceptual capacity. To control for individual differences in cognitive resources, we took a sober record of each participant’s working memory capacity (WMC). Alcohol was expected to impair enumeration performance, either for the automatic...
Vilela, Maria Fernandes, Diana Salazar, Tatiana Sr. Duarte, Augusto
Published in
Cureus
Acute intoxications are common causes of admission to the Emergency Department (ED). Flupirtine is a non-opioid analgesic, originally used for acute and chronic pain. Because of several reports of severe liver toxicity, its use was limited to acute pain in 2013 by the European Medicines Agency. Although withdrawn from the European market in March 2...
Holvoet, Wouter van Soest, Kaja Havenith, Thomas Lorusso, Roberto van Mook, Walther N K A Delnoij, Thijs
Published in
Acta cardiologica
This case report describes an intentional intoxication with 18 g of hydroxychloroquine (HCQ) presenting with unconsciousness, ventricular dysrhythmias, cardiogenic shock and pulmonary oedema. Initial treatment consisted of sodium bicarbonate, lipid emulsion, diazepam and norepinephrine. Because of persistent cardiogenic shock veno-arterial extracor...
Patteet, Lisbeth Maudens, Kristof Wille, Sarah Blanckaert, Peter Neels, Hugo Calle, Paul
Published in
Acta clinica Belgica
Objectives: The content of substances sold and consumed as party drugs is often unknown. They may contain inactive, contaminated or unexpected ingredients, and the dosage of the active components may vary considerably. Obviously, these phenomena increase the chances of a wrong or delayed therapy. To illustrate this point, we report 3 cases of cloza...
Hui, Wun Fung Hon, Kam Lun Leung, Alexander Kc
Published in
Current clinical pharmacology
Poisoning is one of the leading causes of childhood morbidity and mortality worldwide. Despite the advancement of poison detection by modern investigation methods, the clinical skill of toxidrome recognition by combining the findings from a detailed history, thorough physical examination, and the results of basic investigations is still indispensab...
Ríos-Ocampo, W Alfredo Navas, María-Cristina Buist-Homan, Manon Faber, Klaas Nico Daemen, Toos Moshage, Han
Published in
Viruses
Hepatitis C virus (HCV) infection is accompanied by increased oxidative stress and endoplasmic reticulum stress as a consequence of viral replication, production of viral proteins, and pro-inflammatory signals. To overcome the cellular stress, hepatocytes have developed several adaptive mechanisms like anti-oxidant response, activation of Unfolded ...
Sredenšek, Jerneja Bošnjak, Maša Lampreht Tratar, Urša Kosjek, Tina Cemazar, Maja Kržan, Mojca Seliškar, Alenka
Published in
Frontiers in Veterinary Science
An experimental study on the effects of electroporation on pancreatic tissue was performed in pigs, and the fentanyl transdermal patch (FTP) was used postoperatively as part of multimodal pain management. Ingestion of an FTP, which resulted in fentanyl intoxication, was suspected 5 days after placement in one of the experimental pigs. The pig was f...
Pennypacker, Sarah D Romero-Sandoval, E Alfonso
Published in
Pharmacotherapy
Increased public access to cannabis calls for a deeper understanding of cannabis's constituents and how they interact to induce clinical effects. Whereas trans-Δ9 -tetrahydrocannabinol (THC) is considered the main psychoactive component in cannabis, producing the associated "high" or "euphoria," various findings demonstrate medical potential for ca...
Yeh, Ying-Tse Chen, Chun-Kuei Lin, Chih-Chuan Chang, Chia-Ming Lan, Kai-Ping How, Chorng-Kuang Yen, Hung-Tsang Chen, Yen-Chia
Published in
Toxics
The efficacy of hemoperfusion (HP) in patients with acute paraquat poisoning (PQ) remains controversial. We conducted a multi-center retrospective study to include acute PQ-poisoned patients admitted to two tertiary medical centers between 2005 and 2015. We used the Severity Index of Paraquat Poisoning (SIPP) to stratify the severity of PQ-poisoned...