Hedberg, Pär Nohlert, Eva Tegelberg, Åke
Published in
Journal of sleep research
Obstructive sleep apnea (OSA) may lead to increased circulating concentrations of inflammatory biomarkers and treatment may change these. We aimed to assess the effect of oral appliance (OA) therapy on inflammatory biomarkers in a randomised controlled pilot trial. A total of 71 patients with OSA and systemic hypertension were randomly allocated to...
Redenšek, Sara Flisar, Dušan Kojović, Maja Gregorič Kramberger, Milica Georgiev, Dejan Pirtošek, Zvezdan Trošt, Maja Dolžan, Vita
Background: Inflammation and oxidative stress are recognized as important contributors to Parkinson's disease pathogenesis. As such, genetic variability in these pathways could have a role in susceptibility for the disease as well as in the treatment outcome. Dopaminergic treatment is effective in management of motor symptoms, but poses a risk for ...
Kim, Jaejin Lee, Yeonghyeon Jeon, Taerang Kim, Mi-Sung Kang, Chanhee
Published in
Autophagy
Macroautophagy/autophagy is a sophisticated quality control program that limits cellular damage and maintains homeostasis, being an essential part of several lifespan-promoting interventions. However, autophagy is also necessary for full establishment of cellular senescence, a causal factor for many age-related diseases and aging. What lies ahead o...
Yokoe, Yuki Tsuboi, Naotake Imaizumi, Takahiro Kitagawa, Akimitsu Karasawa, Munetoshi Ozeki, Takaya Endo, Nobuhide Sawa, Yuriko Kato, Sawako Katsuno, Takayuki
...
Published in
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
The detection of leukocyte-derived CD11b (α subunit of integrin Mac-1) and CD163 (scavenger receptor) in urine may reflect renal inflammation in antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN). The objective of this study was to evaluate the clinical significance of urinary CD11b (U-CD11b) and CD163 (U-CD163) in ANCA-GN....
Zhou, Jiali He, Wenbo Liang, Jingyu Wang, Lang Yu, Xiaomei Bao, Mingwei Liu, Huafen
Published in
Japanese journal of infectious diseases
The prognostic value of interleukin-6 (IL-6) in coronavirus disease 2019 (COVID-19) needs to be clarified. In this retrospective study, COVID-19 patients treated at Renmin Hospital of Wuhan University from January 7 to February 8, 2020 with measurements of serum IL-6 levels within 1 week after admission were included. Data regarding demographics, c...
Amon, Špela
Življenjski slog vpliva na delovanje prirojenega in pridobljenega imunskega sistema. Eden izmed dejavnikov, ki regulirajo imunski odziv, je prehrana. Z njo vplivamo na črevesno mikrofloro, ki predstavlja pomemben steber obrambe. Za protivnetni učinek moramo zaužiti dovolj kompleksnih ogljikovih hidratov, nenasičenih maščobnih kislin, beljakovin, vi...
Liu, Mingjiang Zhang, Chi Xu, Xiaolong Zhao, Xin Han, Ziyi Liu, Dandan Bo, Ruonan Li, Jingui Liu, Zongping
Published in
Veterinary Research
In bovine mammary epithelial cells (BMECs), a cascade of inflammatory reactions induced by lipopolysaccharide (LPS) has been shown to result in cell injury and apoptosis. The present study aims to reveal the protective effect of ferulic acid (FA) on LPS-induced BMEC apoptosis and explore its potential molecular mechanisms. First, we showed that FA ...
Yeung, Chris Ho Ching Schooling, C Mary
Published in
International journal of epidemiology
Systemic inflammation has been suggested to be associated with Alzheimer's-disease progression, although whether it is a cause or a downstream effect is still controversial. This study aims to assess the effect of systemic inflammatory regulators on Alzheimer's disease within a bidirectional Mendelian-randomization design. Genetic associations with...
Luan, Guangxin Pan, Fan Bu, Lina Wu, Kaixuan Wang, Aizhong Xu, Xiaotao
Published in
Frontiers in Immunology
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is characterized by diffuse inflammation of the lung parenchyma and refractory hypoxemia. Butorphanol is commonly used clinically for perioperative pain relief, but whether butorphanol can regulate LPS-induced alveolar macrophage polarization is unclear. In this study, we observed t...
Liu, Xiaoyu Xu, Yuling Cheng, Saibo Zhou, Xinghong Zhou, Fenghua He, Peikun Hu, Fang Zhang, Lifang Chen, Yuyao Jia, Yuhua
...
Published in
Frontiers in Pharmacology
Inflammation and apoptosis of vascular endothelial cells play a key role in the occurrence and development of atherosclerosis (AS), and the AMPK/mTOR/Nrf2 signaling pathway plays an important role in alleviating the symptoms of AS. Geniposide combined with notoginsenoside R1 (GN combination) is a patented supplement for the prevention and treatment...
