Bogdan, Lucia Barreiro, Luis Bourque, Guillaume
Published in
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Transposable elements (TEs) are increasingly recognized as important contributors to mammalian regulatory systems. For instance, they have been shown to play a role in the human interferon response, but their involvement in other mechanisms of immune cell activation remains poorly understood. Here, we investigated the profile of accessible chromati...
spagnuolo, gianrico de vito, danila rengo, sandro tatullo, marco
Coronavirus disease 2019, also called COVID-19, is the latest infectious disease to rapidly develop worldwide [...]
villalba, lorenzo
Background: The most important series devoted to antithyroid drug-induced severe neutropenia and agranulocytosis are Japanese studies, almost specifically in relation to the intake of methimazole. The clinical data of 30 Caucasian patients followed up for antithyroid drug-induced neutropenia at a third-level hospital are reported. Methods: The data...
malagutti, nicola rotondo, john charles cerritelli, luca melchiorri, claudio de mattei, monica selvatici, rita oton-gonzalez, lucia stomeo, francesco mazzoli, manuela borin, michela
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Background. Previous studies reported human papillomaviruses (HPVs) in middle ear tumors, whereas these viruses have been poorly investigated in chronic inflammatory middle ear diseases. We investigated HPVs in non-tumor middle ear diseases, including chronic otitis media (COM). Methods. COM specimens (n = 52), including chronic suppurative otitis ...
bartnicka, dominika gonzalez-gonzalez, miriam sykut, joanna koziel, joanna ciaston, izabela adamowicz, karina bras, grazyna zawrotniak, marcin karkowska-kuleta, justyna satala, dorota
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Candida albicans is a pathogenic fungus capable of switching its morphology between yeast-like cells and filamentous hyphae and can associate with bacteria to form mixed biofilms resistant to antibiotics. In these structures, the fungal milieu can play a protective function for bacteria as has recently been reported for C. albicans and a periodonta...
colombo, marco gallo, simone poggio, claudio ricaldone, vittorio arciola, carla renata scribante, andrea
The current in vitro study evaluated the Vickers hardness number (VHN) and hardness ratio of four bulk-fill composites (VisCalor bulk / Admira Fusion x-tra / x-tra fil / and GrandioSO x-tra-Voco, Cuxhaven, Germany) to assess the risk of bacterial colonization in comparison with standard composite materials. Thirty samples were prepared for each gro...
Gil, Lidia Łojko-Dankowska, Anna Matuszak, Magdalena Wache, Anna Nowicki, Adam Graduszewska, Anna Niezgoda, Adam Dytfeld, Dominik
Published in
Acta Haematologica Polonica
Chimeric antigen receptor T-cell (CAR-T) therapy is an effective new treatment for hematologic malignancies. Two anti-CD19 CAR-T products, namely axicabtagene ciloleucel and tisagenlecleucel, have been approved for the management of relapsed/refractory large B-cell lymphoma after two lines of systemic therapy. Additionally, tisagenlecleucel is indi...
conza, di
The endoplasmic reticulum (ER) is a critical organelle, storing the majority of calcium and governing protein translation. Thus, it is crucial to keep the homeostasis in all ER components and machineries. The ER stress sensor pathways, including IRE1/sXBP1, PERK/EIf2 and ATF6, orchestrate the major regulatory circuits to ensure ER homeostasis. The ...
caillard, pauline vigneau, cécile halimi, jean-michel hazzan, marc thervet, eric heitz, morgane juillard, laurent audard, vincent rabant, marion hertig, alexandre
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In patients presenting with anti-glomerular basement membrane (GBM) disease with advanced isolated kidney involvement, the benefit of intensive therapy remains controversial due to adverse events, particularly infection. We aim to describe the burden of severe infections (SI) (requiring hospitalization or intravenous antibiotics) and identify predi...
sun, zhong thilakavathy, karuppiah kumar, s. suresh guozhong, he liu, shi v.
Within last 17 years two widespread epidemics of severe acute respiratory syndrome (SARS) occurred in China, which were caused by related coronaviruses (CoVs): SARS-CoV and SARS-CoV-2. Although the origin(s) of these viruses are still unknown and their occurrences in nature are mysterious, some general patterns of their pathogenesis and epidemics a...
