Published in Psychology, health & medicine
Evidence shows that undernutrition during early life is associated with an increased risk of chronic diseases in adulthood. We aimed to investigate whether exposure to the Chinese famine in the fetal or infant stage was associated with self-reported arthritis risk in adulthood. A total of 3,622 participants were included in the final analysis. Part...
Published in AAPS PharmSciTech
Prediction of performance of traditional, reformulated, and novel oral formulations in adults and pediatrics is of great importance. This study was conducted to assess solubility of celecoxib in age-appropriate fasted- and fed-state gastric and intestinal biorelevant media, classify celecoxib into biopharmaceutical classification system (BCS), and ...
Published in Experimental and Therapeutic Medicine
Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal clinical syndrome frequently complicated by acute kidney injury (AKI) and acute tubular necrosis. Renal thrombotic microangiopathy (TMA) is a specific pathological feature of childhood HLH and few cases have been reported among infants. The present study presents a rare case of HLH with T...
Published in Frontiers in Pediatrics
Langerhans cell histiocytosis (LCH) is a rare disease with uncertain etiology. Langerhans cell histiocytosis with involvement of the gastrointestinal tract is rare and is typically identified in pediatric patients with systemic disease. The present study reports two infantile cases of LCH who initially presented with diarrhea, hematochezia, and ras...
V magistrski nalogi smo preučevali dejavnike aktivnega očetovstva v Sloveniji. V vzorec smo vključili 194 očetov, ki so imeli dojenčka, starega od nič do enega leta, bili zaposleni in živeli skupaj s svojo partnerko ter dojenčkom. Njihova povprečna starost je bila 31 let, povprečna starost njihovih dojenčkov pa sedem mesecev. Večina očetov (73,2 %)...
Published in Nutrients
Small and nutritionally at-risk infants under six months, defined as those with wasting, underweight, or other forms of growth failure, are at high-risk of mortality and morbidity. The World Health Organisation 2013 guidelines on severe acute malnutrition highlight the need to effectively manage this vulnerable group, but programmatic challenges ar...
Published in International Medical Case Reports Journal
Background Leeches are blood sucking hermaphroditic parasites belonged to the phylum Annelida of the class Hirudinea. Based on the location of leech infestation, the patient may present with anemia and respiratory symptoms. Even though Leech infestation is mentioned as common problem in African countries and the common cause of anemia, especially i...
Published in Frontiers in Pediatrics
Objective: The clinical symptoms of neonatal Prader-Willi syndrome (PWS) are not typical and are easy to miss. The aim of the study was to investigate the clinical features and genetic characteristics of seven cases of neonatal PWS from northern China, and to improve the understanding of PWS in neonates. Methods: We retrospectively analyzed seven i...
Published in Frontiers in Pediatrics
Background: Birth cohorts provided essential knowledge for clinical and public health decision-making. However, little is known about retention and determinants of attrition in these specific longitudinal studies, although characterizing predictors of attrition sets the path to mitigate its occurrence and to promote valid inferences. We systematica...
Published in Frontiers in Immunology
Human B-lymphopoiesis is a dynamic life-long process that starts in utero by around six post-conception weeks. A detailed understanding of human fetal B-lymphopoiesis and how it changes in postnatal life is vital for building a complete picture of normal B-lymphoid development through ontogeny, and its relevance in disease. B-cell acute lymphoblast...
